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CSF1R 产品

(Colony Stimulating Factor 1 Receptor (CSF1R))
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008].

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Featured CSF1R Categories

CSF1R 抗体

High quality antibodies with extensive validation data.

CSF1R ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CSF1R 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CSF1R 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (6)
Cat. No. ABIN1724928
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
  • (2)
  • (6)
Cat. No. ABIN1724925
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human
Application WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro)
Validations
  • (1)
  • (1)
  • (1)
Cat. No. ABIN683788
Quantity 100 μL
Datasheet Datasheet

Recommended CSF1R ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965974
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973799
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973405
Quantity 96 tests
Datasheet Datasheet

Recommended CSF1R 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274424
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274422
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274428
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CSF1R Products

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Bellora, Dondero, Corrias, Casu, Regis, Caliendo, Moretta, Cazzola, Elena, Vinti, Locatelli, Bottino, Castriconi: "Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1516-1525, (2017) (PubMed).

Lundgren, Martinsson, Cederbrant, Jirholt, Mucs, Madeyski-Bengtson, Havarinasab, Hultman: "HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicity." in: PLoS ONE, Vol. 12, Issue 9, pp. e0184744, (2017) (PubMed).

Baj-Krzyworzeka, Mytar, Szatanek, Surmiak, Węglarczyk, Baran, Siedlar: "Colorectal cancer-derived microvesicles modulate differentiation of human monocytes to macrophages." in: Journal of translational medicine, Vol. 14, pp. 36, (2016) (PubMed).

Devêvre, Renovato-Martins, Clément, Sautès-Fridman, Cremer, Poitou: "Profiling of the three circulating monocyte subpopulations in human obesity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3917-23, (2015) (PubMed).

Gorden, Saha, Khammanivong, Schwartz, Dickerson: "Lysosomal drug sequestration as a mechanism of drug resistance in vascular sarcoma cells marked by high CSF-1R expression." in: Vascular cell, Vol. 6, pp. 20, (2014) (PubMed).

Moffat, Rothwell, Garcia-Morales, Sauter, Kapetanovic, Gow, Hume: "Development and characterisation of monoclonal antibodies reactive with porcine CSF1R (CD115)." in: Developmental and comparative immunology, Vol. 47, Issue 1, pp. 123-8, (2014) (PubMed).

Weidenaar, Ter Elst, Kampen, Meeuwsen-de Boer, Kamps, Schuringa, de Bont: "Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584." in: Molecular cancer research : MCR, Vol. 11, Issue 4, pp. 339-48, (2014) (PubMed).

Król, Majchrzak, Mucha, Homa, Bulkowska, Jakubowska, Karwicka, Paw?owski, Motyl: "CSF-1R as an inhibitor of apoptosis and promoter of proliferation, migration and invasion of canine mammary cancer cells." in: BMC veterinary research, Vol. 9, pp. 65, (2013) (PubMed).

Kapetanovic, Fairbairn, Downing, Beraldi, Sester, Freeman, Tuggle, Archibald, Hume: "The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide." in: BMC genomics, Vol. 14, pp. 581, (2013) (PubMed).

Synonyms and alternative names related to CSF1R

colony stimulating factor 1 receptor (Csf1r), colony stimulating factor 1 receptor (CSF1R), macrophage colony-stimulating factor receptor (m-csfr), colony stimulating factor 1 receptor (csf1r), colony stimulating factor 1 receptor, a (csf1ra), AI323359, C-FMS, c-fms, CD115, CSF-1-R, CSF-1R, CSF1, csf1r, Csfmr, CSFR, Fim-2, FIM2, Fms, FMS, fms, HDLS, M-CSF, M-CSF-R, M-CSFR, MGC89146, mrfms, panther, PDGFRB

Protein level used designations for CSF1R

  • CSF-1 receptor
  • CSF-1-R
  • c-fms
  • macrophage colony-stimulating factor 1 receptor
  • proto-oncogene c-Fms
  • proto-oncogene fms
  • CD115 antigen
  • FMS proto-oncogene
  • McDonough feline sarcoma viral (v-fms) oncogene homolog
  • macrophage colony stimulating factor I receptor
  • colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog
  • platelet-derived growth factor receptor, beta polypeptide
  • protein-tyrosine kinase
  • macrophage colony-stimulating factor receptor
  • csf1r protein
  • colony stimulating factor 1 receptor
  • macrophage colony-stimulating factor 1 receptor-like
  • fms proto-oncogene
  • fms proto-oncogene homolog
  • proto-oncogene c-Fms homolog
  • proto-oncogene fms homolog
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