CRBN 抗体
(Cereblon (CRBN))
This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
recommended
recommended
recommended
CRBN 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, 猴, Pig, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
CRBN 抗体 by 应用范围
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CRBN 抗体 by 抗体来源
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CRBN 抗体 by 抗原表位
Find CRBN 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
CRBN 抗体 by 克隆形成能力
Find available monoclonal or polyclonal CRBN 抗体. Click on a link to go to the corresponding products.
Popular CRBN 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7165198
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN526543
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1387716
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1392919
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392917
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392916
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392915
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392918
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN2808550
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5000487
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5000486
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392920
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1410807
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1410808
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our CRBN 抗体
: "Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome." in: eLife, Vol. 7, (2019) (PubMed).: "Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs." in: Bioorganic & medicinal chemistry, Vol. 27, Issue 12, pp. 2466-2479, (2019) (PubMed).
: "Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations." in: Nature communications, Vol. 10, Issue 1, pp. 3468, (2019) (PubMed).
: "Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of ..." in: Journal of medicinal chemistry, (2018) (PubMed).
: "Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation." in: Nature chemical biology, Vol. 14, Issue 2, pp. 163-170, (2018) (PubMed).
: "Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, (2014) (PubMed).
: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, (2014) (PubMed).
: "Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity." in: British journal of haematology, Vol. 164, Issue 2, pp. 233-44, (2014) (PubMed).
: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, (2011) (PubMed).
: "pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBNubiquitin ligase." in: Nature communications, Vol. 8, pp. 15398 (PubMed).
Aliases for CRBN 抗体
cereblon (crbn) 抗体cereblon (CRBN) 抗体
ATP-dependent protease La (LON) domain protein (AT2G25740) 抗体
cereblon (Crbn) 抗体
2610203G15Rik 抗体
2900045O07Rik 抗体
AF229032 抗体
AW108261 抗体
F3N11.21 抗体
MRT2 抗体
mrt2a 抗体
MRT2A 抗体
piL 抗体
zgc:92404 抗体
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