COX10 产品
(Cytochrome C Oxidase Assembly Homolog 10 (COX10))
Categories
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008].
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Featured COX10 Categories
Recommended COX10 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN654671
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (3)
Cat. No.
ABIN2782122
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN951674
Quantity
0.4 mL
Datasheet
Datasheet
Recommended COX10 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6235105
Quantity
96 tests
Datasheet
Datasheet
Recommended COX10 蛋白
Synonyms and alternative names related to COX10
cytochrome c oxidase assembly protein 10 (Cox10), COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor (cox10), COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog (cox10.L), COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor (COX10), cytochrome c oxidase 10 (COX10), protoheme IX farnesyltransferase, mitochondrial (LOC100732273), COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor (Cox10), 2410004F01Rik, AU042636, Cox10, cytochrome c oxidase 10, F4I1.50, F4I1_50, im:7145568, im:7157205, wu:fb18a03Protein level used designations for COX10
- COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase
- heme O synthase
- protoheme IX farnesyltransferase, mitochondrial
- cytochrome c oxidase assembly protein
- cytochrome c oxidase subunit X
- heme A: farnesyltransferase
- heme A:farnesyltransferase
- cytochrome c oxidase assembly homolog 10
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