Cortactin 抗体
(Cortactin (CTTN))
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
recommended
Cortactin 抗体 (N-Term) (ABIN2854674)
KO Validated CTTN 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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- (1)
Cat. No.
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Quantity
100 μL
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Quantity
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WB, ELISA, IF, ICC
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Application
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Cat. No.
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Quantity
100 μg
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Datasheet
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Application
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Cat. No.
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Quantity
100 μg
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Datasheet
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Application
WB, ELISA
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Quantity
100 μL
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Datasheet
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Application
IHC
Validations
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Cat. No.
ABIN7258326
Quantity
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Datasheet
Datasheet
Latest Publications for our Cortactin 抗体
: "Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases." in: Molecular biology of the cell, Vol. 20, Issue 14, pp. 3209-23, (2009) (PubMed).: "Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells." in: Cell and tissue research, Vol. 337, Issue 1, pp. 91-102, (2009) (PubMed).
: "[Expression and clinical significance of EMS1 gene in gastric carcinoma]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 27, Issue 3, pp. 323-6, (2008) (PubMed).
: "Association of cortactin, fascin-1 and epidermal growth factor receptor (EGFR) expression in ovarian carcinomas: correlation with clinicopathological parameters." in: Disease markers, Vol. 25, Issue 1, pp. 17-26, (2008) (PubMed).
: "The development of a minimal intervention strategy to address overweight and obesity in adult primary care patients in The Netherlands." in: Family practice, Vol. 25 Suppl 1, pp. i112-5, (2008) (PubMed).
: "Cortactin in tumor invasiveness." in: Cancer letters, Vol. 265, Issue 2, pp. 157-66, (2008) (PubMed).
: "Cortactin branches out: roles in regulating protrusive actin dynamics." in: Cell motility and the cytoskeleton, Vol. 65, Issue 9, pp. 687-707, (2008) (PubMed).
: "Tubedown associates with cortactin and controls permeability of retinal endothelial cells to albumin." in: Journal of cell science, Vol. 121, Issue Pt 12, pp. 1965-72, (2008) (PubMed).
: "Roles of cortactin in tumor pathogenesis." in: Biochimica et biophysica acta, Vol. 1775, Issue 2, pp. 263-73, (2007) (PubMed).
: "CXCL12 induces tyrosine phosphorylation of cortactin, which plays a role in CXC chemokine receptor 4-mediated extracellular signal-regulated kinase activation and chemotaxis." in: The Journal of biological chemistry, Vol. 281, Issue 40, pp. 30081-93, (2006) (PubMed).
Aliases for Cortactin 抗体
cortactin (CTTN) 抗体cortactin (Cttn) 抗体
CG3637 gene product from transcript CG3637-RD (Cortactin) 抗体
cortactin S homeolog (cttn.S) 抗体
cortactin L homeolog (cttn.L) 抗体
cortactin (cttn) 抗体
src substrate cortactin (CpipJ_CPIJ006351) 抗体
Src substrate cortactin (Bm1_57220) 抗体
cortactin (LOC100533277) 抗体
1110020L01Rik 抗体
CG3637 抗体
cortactin 抗体
cttn 抗体
Cttn 抗体
CTTN 抗体
CTTN1 抗体
Cttnb 抗体
Dmel\CG3637 抗体
EMS1 抗体
Ems1 抗体
ems1 抗体
P85.25 抗体
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