COPS7B 产品
(COP9 Signalosome Complex Subunit 7b (COPS7B))
Categories
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively (By similarity).
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Featured COPS7B Categories
Recommended COPS7B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7148503
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN6243119
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN528678
Quantity
50 μg
Datasheet
Datasheet
Recommended COPS7B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350066
Quantity
10 μg
Datasheet
Datasheet
Synonyms and alternative names related to COPS7B
COP9 signalosome subunit 7B (Cops7b), COP9 signalosome subunit 7B (COPS7B), COP9 signalosome subunit 7B S homeolog (cops7b.S), CSN7B, D1Wsu66e, E130114M23, MGC114836Protein level used designations for COPS7B
- COP9 (constitutive photomorphogenic) homolog, subunit 7b
- COP9 constitutive photomorphogenic homolog subunit 7B
- COP9 signalosome complex subunit 7b
- COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
- COP9 constitutive photomorphogenic subunit 7B
- COP9 complex S7b
- JAB1-containing signalosome subunit 7b
- SGN7b
- signalosome subunit 7b
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