COPS5 抗体
(COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008].
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COPS5 抗体 by 应用范围
Find COPS5 抗体 validated for a specific application such as WB, IHC, IHC (p), IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.
COPS5 抗体 by 抗体来源
Find COPS5 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
COPS5 抗体 by 抗原表位
Find COPS5 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
COPS5 抗体 by 克隆形成能力
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COPS5 抗体 by 克隆
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Popular COPS5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, ChIP
Validations
- (7)
Cat. No.
ABIN7266497
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN3022512
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN6138883
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7259711
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (3)
Cat. No.
ABIN7256932
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6260970
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN3042754
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7235241
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6735871
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), IP
Validations
- (2)
Cat. No.
ABIN337275
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN685912
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6242680
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6742215
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IHC (p), IP
Validations
- (1)
Cat. No.
ABIN214239
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (2)
Cat. No.
ABIN2777332
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our COPS5 抗体
: "Nedd8 hydrolysis by UCH proteases in Plasmodium parasites." in: PLoS pathogens, Vol. 15, Issue 10, pp. e1008086, (2019) (PubMed).: "COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9299-309, (2015) (PubMed).
: "COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels." in: The Journal of biological chemistry, Vol. 288, Issue 37, pp. 26668-77, (2013) (PubMed).
: "The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E577-85, (2011) (PubMed).
: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).
: "Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development." in: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5621-33, (2008) (PubMed).
: "The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12557-65, (2007) (PubMed).
: "Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif." in: FEBS letters, Vol. 579, Issue 7, pp. 1693-701, (2005) (PubMed).
: "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase." in: Nature cell biology, Vol. 6, Issue 12, pp. 1229-35, (2004) (PubMed).
: "Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31296-303, (2004) (PubMed).
Aliases for COPS5 抗体
COP9 signalosome subunit 5 (CSN5) 抗体COP9 signalosome subunit 5 (COPS5) 抗体
COP9 signalosome subunit 5 (cops5) 抗体
COP9 signalosome complex subunit 5 (CpipJ_CPIJ012314) 抗体
COP9 signalosome complex subunit 5 (Bm1_46585) 抗体
COP9 signalosome complex subunit 5 (VDBG_06932) 抗体
COP9 signalosome complex subunit 5 (LOAG_01443) 抗体
COP9 signalosome complex subunit 5 (csn5) 抗体
COP9 signalosome subunit 5 (Cops5) 抗体
COP9 signalosome subunit 5 S homeolog (cops5.S) 抗体
COP9 signalosome complex subunit 5 (csn-5) 抗体
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COPS5 抗体
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csn5 抗体
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Dch5 抗体
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Dmel\\CG14884 抗体
JAB1 抗体
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jab1/csn5 抗体
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