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COPS2 抗体

(Alien (COPS2))
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis.

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Featured COPS2 Categories

COPS2 抗体

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to COPS2

CG9556 gene product from transcript CG9556-RD (alien), Alien, BcDNA:LD10463, CG9556, CH2, CSN2, Csn2, DCH2, Dch2, Dmel\\CG9556

Protein level used designations for COPS2

  • CG9556-PA
  • CG9556-PB
  • CG9556-PD
  • COP9 complex homolog subunit 2
  • alien-PA
  • alien-PB
  • alien-PD
  • d-Alien
  • drosophila COP9 signalosome homolog 2
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