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COPRS 产品

(Coordinator of PRMT5, Differentiation Stimulator (COPRS))
Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression (By similarity).

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Featured COPRS Categories

COPRS ELISA试剂盒

Reliable ELISA kits for a wide range of species.

COPRS 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COPRS ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955067
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5653315
Quantity 96 tests
Datasheet Datasheet

Recommended COPRS 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7410052
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3128232
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6378769
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our COPRS Products

Strahan, McDowell-Sargent, Uppal, Purushothaman, Verma: "KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation." in: PLoS pathogens, Vol. 13, Issue 7, pp. e1006482, (2017) (PubMed).

Mongiardi, Savino, Bartoli, Beji, Nanni, Scagnoli, Falchetti, Favia, Farsetti, Levi, Nasi, Illi: "Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells." in: Scientific reports, Vol. 5, pp. 15494, (2015) (PubMed).

Synonyms and alternative names related to COPRS

coordinator of PRMT5 and differentiation stimulator (COPRS), coordinator of PRMT5, differentiation stimulator (Coprs), 1700029I03Rik, 2410022L05Rik, AA409325, AI256813, C17orf79, C19H17orf79, C85432, COPR5, Copr5, HSA272196, TTP1

Protein level used designations for COPRS

  • cooperator of PRMT5
  • coordinator of PRMT5 and differentiation stimulator
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