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Complement C5b 产品

(Complement C5 beta Chain (C5b))

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The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].

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Featured Complement C5b Categories

Complement C5b ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended Complement C5b 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC (fro)
Validations
Cat. No. ABIN284013
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Goat, Human, Pig, Primate
Application ELISA, WB, IHC
Validations
Cat. No. ABIN5954788
Quantity 50 μg
Datasheet Datasheet

Recommended Complement C5b ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966049
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962122
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative
Validations
  • (1)
Cat. No. ABIN1052365
Quantity 96 tests
Datasheet Datasheet

Synonyms and alternative names related to Complement C5b

complement C5 (C5), C5a, C5b, CPAMD4

Protein level used designations for Complement C5b

  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
  • C5a anaphylatoxin
  • anaphylatoxin C5a analog
  • complement C5
  • prepro-C5
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