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COMP 蛋白

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
COMP Protein (C-Term) COMP Protein (C-Term) COMP Protein (C-Term) (ABIN1047991)

COMP 宿主: 大鼠 Recombinant > 95 % (SDS-PAGE)

COMP Protein (AA 22-240) (GST-His-Tag) (ABIN7505321)

COMP 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

COMP Protein (AA 123-240) (His tag) (ABIN7393391)

COMP 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, SDS, Imm, PC

COMP 蛋白 by Origin

Find COMP 蛋白 for a variety of species such as anti-Human COMP, anti-Rat COMP, anti-Mouse COMP. The species listed below are among those available. Click on a link to go to the corresponding products.

COMP 蛋白 by Source

Here you will find COMP 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

COMP 蛋白 by 蛋白类型

Here you can find COMP 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

COMP 蛋白 by 应用范围

Find COMP 蛋白 validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

COMP 蛋白 by 生物活性

Find COMP 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular COMP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source
Validations
  • (1)
  • (1)
Cat. No. ABIN1047991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505321
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393391
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421479
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393394
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402583
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402586
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393397
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403273
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7534406
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2180897
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008640
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712452
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN1061972
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our COMP 蛋白

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliases for COMP 蛋白

cartilage oligomeric matrix protein (COMP) 蛋白
cartilage oligomeric matrix protein (sce3551) 蛋白
cartilage oligomeric matrix protein (CJA_1292) 蛋白
cartilage oligomeric matrix protein (Comp) 蛋白
COMP 蛋白
EDM1 蛋白
EPD1 蛋白
MED 蛋白
PSACH 蛋白
THBS5 蛋白
TSP5 蛋白
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