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COL18A1 产品

(Collagen, Type XVIII, alpha 1 (COL18A1))
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

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Featured COL18A1 Categories

COL18A1 抗体

High quality antibodies with extensive validation data.

COL18A1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

COL18A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COL18A1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (2)
Cat. No. ABIN669951
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7445252
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Human
Application WB, IHC, IF/ICC
Validations
  • (3)
Cat. No. ABIN2982659
Quantity 100 μL
Datasheet Datasheet

Recommended COL18A1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN6954970
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6954969
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966496
Quantity 96 tests
Datasheet Datasheet

Recommended COL18A1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320492
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Synthetic
Validations
  • (2)
Cat. No. ABIN1880228
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Yeast (Pichia pastoris)
Validations
Cat. No. ABIN987805
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our COL18A1 Products

Salem, Wadie: "Effect of Niacin on Inflammation and Angiogenesis in a Murine Model of Ulcerative Colitis." in: Scientific reports, Vol. 7, Issue 1, pp. 7139, (2019) (PubMed).

Yu, Lu, Li, Zhou, Zeng, Zhan, Yuan, Yang, Xia: "Correlation of Plasma Vascular Endothelial Growth Factor and Endostatin Levels with Symptomatic Intra- and Extracranial Atherosclerotic Stenosis in a Chinese Han Population." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 26, Issue 5, pp. 1061-1070, (2017) (PubMed).

Silva, Almeida, Teixeira, Oliveira, Vasconcelos: "Impaired angiogenesis as a feature of digital ulcers in systemic sclerosis." in: Clinical rheumatology, Vol. 35, Issue 7, pp. 1743-51, (2016) (PubMed).

Imoto, Kumatani, Okada, Yamawaki: "Endostatin is protective against monocrotaline-induced right heart disease through the inhibition of T-type Ca(2+) channel." in: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 7, pp. 1259-70, (2016) (PubMed).

Foster, Farragher, Parker, Sosa: "Treatment Interventions for Early Childhood Obesity: A Systematic Review." in: Academic pediatrics, Vol. 15, Issue 4, pp. 353-61, (2015) (PubMed).

Peng, Gao, Jiang, Wang, Zhang, Xiao, Ou, Yang, Yang, Xiao: "ANGIOGENESIS INHIBITOR ENDOSTATIN PROTECTS MICE WITH SEPSIS FROM MULTIPLE ORGAN DYSFUNCTION SYNDROME." in: Shock (Augusta, Ga.), Vol. 44, Issue 4, pp. 357-64, (2015) (PubMed).

Etulain, Mena, Negrotto, Schattner: "Stimulation of PAR-1 or PAR-4 promotes similar pattern of VEGF and endostatin release and pro-angiogenic responses mediated by human platelets." in: Platelets, Vol. 26, Issue 8, pp. 799-804, (2015) (PubMed).

Hu, Hu, Zhang, Jia, Qian, Yang, Li: "Clinical significance of serum and tumor tissue endostatin evaluation in operable non-small cell lung cancer." in: Biomedical reports, Vol. 2, Issue 6, pp. 898-904, (2014) (PubMed).

Zhang, Yu, Lu, Xia, Xie, Hu, Hao, Xu, Qian: "Prognostic values of VEGF and endostatin with malignant pleural effusions in patients with lung cancer." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 15, Issue 19, pp. 8435-40, (2014) (PubMed).

Biswal, Prentice, Dorey, Blanks: "A hypoxia-responsive glial cell-specific gene therapy vector for targeting retinal neovascularization." in: Investigative ophthalmology & visual science, Vol. 55, Issue 12, pp. 8044-53, (2014) (PubMed).

Synonyms and alternative names related to COL18A1

collagen type XVIII alpha 1 chain (COL18A1), collagen type XVIII alpha 1 chain a (col18a1a), collagen type XVIII alpha 1 chain (Col18a1), collagen, type XVIII, alpha 1 (COL18A1), collagen type XVIII alpha 1 (col18a1), collagen, type XVIII, alpha 1 (Col18a1), cb371, cb529, fc96d06, KNO, kno, KNO1, kno1, KS, sb:cb529, wu:fb47h10, wu:fb77g12, wu:fc50f04, wu:fc96d06, wu:fk02h12

Protein level used designations for COL18A1

  • antiangiogenic agent
  • collagen alpha-1(XVIII) chain
  • endostatin
  • multi-functional protein MFP
  • procollagen, type XVIII, alpha 1
  • collagen, type XVIII, alpha 1
  • alpha 1 type XVIII collagen
  • collagen alpha-1(XVIII) chain-like
  • LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain
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