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COCH 抗体

(Cochlin (COCH))
The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq, Oct 2008].
COCH 抗体  (AA 20-260) COCH 抗体  (AA 20-260) COCH 抗体 (AA 20-260) (ABIN7148039)

COCH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

COCH 抗体 COCH 抗体 COCH 抗体 (ABIN7262425)

COCH 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated

COCH 抗体  (AA 1-494) COCH 抗体  (AA 1-494) COCH 抗体 (AA 1-494) (ABIN514965)

COCH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

COCH 抗体 by 适用

Find COCH 抗体 for a variety of species such as anti-Human COCH, anti-Mouse COCH, anti-Rat COCH. The species listed below are among those available. Click on a link to go to the corresponding products.

COCH 抗体 by 应用范围

Find COCH 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

COCH 抗体 by 抗体来源

Find COCH 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

COCH 抗体 by 抗原表位

Find COCH 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

COCH 抗体 by 克隆形成能力

Find available monoclonal or polyclonal COCH 抗体. Click on a link to go to the corresponding products.

COCH 抗体 by 克隆

Find COCH 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

COCH 抗体 by 标记

Find COCH 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular COCH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7148039
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (2)
Cat. No. ABIN7262425
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN514965
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Rabbit, Rat
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN6746617
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (2)
Cat. No. ABIN6138819
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN656833
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN951612
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7148038
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6746616
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN929280
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN655279
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2788126
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2788127
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (2)
Cat. No. ABIN951613
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF
Validations
Cat. No. ABIN6759780
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our COCH 抗体

Jung, Yoo, Choe, Park, Lee, Lee, Noh, Kim, Kang, Lee, Yoon, Jang, Yoon, Hyun, Choi: "Cleaved Cochlin Sequesters Pseudomonas aeruginosa and Activates Innate Immunity in the Inner Ear." in: Cell host & microbe, Vol. 25, Issue 4, pp. 513-525.e6, (2019) (PubMed).

Anfosso, Bardin, Francès, Vivier, Camoin-Jau, Sampol, Dignat-George: "Activation of human endothelial cells via S-endo-1 antigen (CD146) stimulates the tyrosine phosphorylation of focal adhesion kinase p125(FAK)." in: The Journal of biological chemistry, Vol. 273, Issue 41, pp. 26852-6, (1998) (PubMed).

Jean, Gershenwald, Huang, Luca, Hudson, Tainsky, Bar-Eli: "Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 26, pp. 16501-8, (1998) (PubMed).

Xie, Luca, Huang, Gutman, Reich, Johnson, Bar-Eli: "Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis." in: Cancer research, Vol. 57, Issue 11, pp. 2295-303, (1997) (PubMed).

Lehmann, Riethmüller, Johnson: "MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 24, pp. 9891-5, (1990) (PubMed).

Aliases for COCH 抗体

cochlin (Coch) 抗体
cochlin (COCH) 抗体
AW122937 抗体
Coch-5B2 抗体
COCH-5B2 抗体
COCH5B2 抗体
D12H14S564E 抗体
DFNA9 抗体
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