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Coagulation Factor IX 产品

(Coagulation Factor IX (F9))

Categories

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq, Jul 2008].

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Featured Coagulation Factor IX Categories

Coagulation Factor IX 抗体

High quality antibodies with extensive validation data.

Coagulation Factor IX ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Coagulation Factor IX 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Coagulation Factor IX 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, RNAi
Validations
  • (5)
Cat. No. ABIN560826
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN3022174
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7147989
Quantity 100 μg
Datasheet Datasheet

Recommended Coagulation Factor IX ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963491
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954868
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965889
Quantity 96 tests
Datasheet Datasheet

Recommended Coagulation Factor IX 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353331
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353329
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
Cat. No. ABIN7505722
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Coagulation Factor IX Products

Lin, Gu, Zhou, Wang, Guo, Chen, Ma, Xiao, Wang, Tian: "Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy." in: Frontiers in neuroscience, Vol. 14, pp. 737, (2020) (PubMed).

Gaul, Weber, van Tits, Sluka, Pasterk, Reiner, Calatayud, Lohmann, Klingenberg, Pahla, Vdovenko, Tanner, Camici, Eriksson, Auwerx, Mach, Windecker, Rodondi, Lüscher, Winnik, Matter: "Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity." in: Cardiovascular research, Vol. 114, Issue 8, pp. 1178-1188, (2018) (PubMed).

Yang, Bae, Jung, Park, Chung, Seok, Roh, Han, Oh, Sohn, Jeong, Cho: "Surface functionalization-specific binding of coagulation factors by zinc oxide nanoparticles delays coagulation time and reduces thrombin generation potential in vitro." in: PLoS ONE, Vol. 12, Issue 7, pp. e0181634, (2017) (PubMed).

Li, Wang, Long, Su, Bukhory, Dai, Jin, Huang, Jia, Li, Fan, Liu, Wang: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." in: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).

Bertina: "Elevated clotting factor levels and venous thrombosis." in: Pathophysiology of haemostasis and thrombosis, Vol. 33, Issue 5-6, pp. 395-400, (2005) (PubMed).

Pipe: "Coagulation factors with improved properties for hemophilia gene therapy." in: Seminars in thrombosis and hemostasis, Vol. 30, Issue 2, pp. 227-37, (2004) (PubMed).

Bogdanov, Balasubramanian, Hathcock, Vele, Lieb, Nemerson: "Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein." in: Nature medicine, Vol. 9, Issue 4, pp. 458-62, (2003) (PubMed).

Synonyms and alternative names related to Coagulation Factor IX

adenylate kinase 3 (Ak3), coagulation factor IX (F9), coagulation factor IXa (f9a), coagulation factor 9 (f9), coagulation factor IX (CpipJ_CPIJ003776), coagulation factor IX (CpipJ_CPIJ009129), coagulation factor IX (CpipJ_CPIJ013063), coagulation factor IX (CpipJ_CPIJ013624), coagulation factor IX (Tsp_01441), coagulation factor 9 S homeolog (f9.S), Coagulation factor IX (fa9), coagulation factor IXb (f9b), AA407498, AI506714, AK-3, Ak3l, Ak3l1, Akl3l, AW111646, Cf-9, Cf9, f9, FIX, fix, FIXA, HEMB, hemb, P19, PTC, ptc, THPH8, zgc:109775, zgc:136807

Protein level used designations for Coagulation Factor IX

  • AK 3
  • GTP:AMP phosphotransferase AK3, mitochondrial
  • GTP:AMP phosphotransferase mitochondrial
  • GTP:AMP phosphotransferase, mitochondrial
  • adenylate kinase 3 alpha-like 1
  • Christmas factor
  • F9 p22
  • FIX F9
  • factor 9
  • factor IX F9
  • plasma thromboplastic component
  • plasma thromboplastin component
  • factor IX
  • christmas factor
  • Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)
  • coagulation factor 9
  • coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)
  • coagulation factor IX
  • factor IX activated protein
  • coagulation factor 9 (plasma thromboplastic component, Christmas disease, hemophilia B)
  • gla domain
  • Coagulation factor IX
  • coagulation factor IX-like
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