CNTNAP2 抗体
(Contactin Associated Protein-Like 2 (CNTNAP2))
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.[provided by RefSeq, Mar 2010].
recommended
recommended
CNTNAP2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
recommended
CNTNAP2 抗体 by 适用
Find CNTNAP2 抗体 for a variety of species such as anti-Human CNTNAP2, anti-Rat CNTNAP2, anti-Mouse CNTNAP2. The species listed below are among those available. Click on a link to go to the corresponding products.
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Datasheet
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Reactivity
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Application
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Quantity
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Datasheet
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Latest Publications for our CNTNAP2 抗体
: "Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 19, pp. 6176-81, (2015) (PubMed).: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).
: "Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture." in: Nature, Vol. 500, Issue 7461, pp. 217-21, (2013) (PubMed).
: "Morvan syndrome: clinical and serological observations in 29 cases." in: Annals of neurology, Vol. 72, Issue 2, pp. 241-55, (2012) (PubMed).
: "Clustering and activity tuning of Kv1 channels in myelinated hippocampal axons." in: The Journal of biological chemistry, Vol. 286, Issue 29, pp. 25835-47, (2011) (PubMed).
: "Molecular microdomains in a sensory terminal, the vestibular calyx ending." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 27, pp. 10101-14, (2011) (PubMed).
: "Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome." in: European journal of human genetics : EJHG, Vol. 19, Issue 2, pp. 186-93, (2011) (PubMed).
: "Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 7, pp. 2480-9, (2010) (PubMed).
: "Human myelin proteome and comparative analysis with mouse myelin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 34, pp. 14605-10, (2009) (PubMed).
Aliases for CNTNAP2 抗体
contactin associated protein like 2 (CNTNAP2) 抗体contactin associated protein-like 2 (Cntnap2) 抗体
contactin associated protein-like 2 (CNTNAP2) 抗体
contactin associated protein like 2b (cntnap2b) 抗体
contactin associated protein like 2 (cntnap2) 抗体
contactin associated protein like 2 (Cntnap2) 抗体
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