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CNTNAP1 产品

(Contactin Associated Protein 1 (CNTNAP1))
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009].

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Featured CNTNAP1 Categories

CNTNAP1 抗体

High quality antibodies with extensive validation data.

CNTNAP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CNTNAP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CNTNAP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7148481
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
  • (2)
Cat. No. ABIN1386083
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7148482
Quantity 100 μg
Datasheet Datasheet

Recommended CNTNAP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962303
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512446
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN778361
Quantity 96 tests
Datasheet Datasheet

Recommended CNTNAP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349901
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406137
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416952
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CNTNAP1 Products

McGonigal, Barrie, Yao, Black, McLaughlin, Willison: "Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice." in: Journal of neurochemistry, (2021) (PubMed).

Sharma, Chakravarthy, Suresh, Devanathan: "Adult Goat Retinal Neuronal Culture: Applications in Modeling Hyperglycemia." in: Frontiers in neuroscience, Vol. 13, pp. 983, (2019) (PubMed).

Jenkins, Kim, Jones, Tseng, Svitkina, Yin, Bennett: "Giant ankyrin-G: a critical innovation in vertebrate evolution of fast and integrated neuronal signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 4, pp. 957-64, (2015) (PubMed).

Hinman, Lee, Tung, Vinters, Carmichael: "Molecular disorganization of axons adjacent to human lacunar infarcts." in: Brain : a journal of neurology, Vol. 138, Issue Pt 3, pp. 736-45, (2015) (PubMed).

Chen, Koopmans, Gordon, Paliukhovich, Klaassen, van der Schors, Peles, Verhage, Smit, Li: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).

DEste, Kamin, Göttfert, El-Hady, Hell: "STED nanoscopy reveals the ubiquity of subcortical cytoskeleton periodicity in living neurons." in: Cell reports, Vol. 10, Issue 8, pp. 1246-51, (2015) (PubMed).

Zollinger, Chang, Baalman, Kim, Rasband: "The Polarity Protein Pals1 Regulates Radial Sorting of Axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 29, pp. 10474-84, (2015) (PubMed).

Hirono, Ogawa, Misono, Zollinger, Trimmer, Rasband, Misonou: "BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7082-94, (2015) (PubMed).

Xing, Röth, Stratton, Chuang, Danne, Ellis, Ng, Kilpatrick, Merson: "Adult neural precursor cells from the subventricular zone contribute significantly to oligodendrocyte regeneration and remyelination." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 42, pp. 14128-46, (2014) (PubMed).

Dagley, White, Liao, Shi, Smyth, Orian, Emili, Purcell: "Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain." in: Proteomics, Vol. 14, Issue 2-3, pp. 241-61, (2014) (PubMed).

Synonyms and alternative names related to CNTNAP1

contactin associated protein 1 (CNTNAP1), contactin associated protein 1 (cntnap1), contactin associated protein 1 (Cntnap1), contactin associated protein-like 1 (Cntnap1), AI841080, CASPR, Caspr, CNTNAP, CNTNAP1, NCP1, NRXN4, Nrxn4, P190, p190, shm

Protein level used designations for CNTNAP1

  • contactin associated protein 1
  • contactin-associated protein 1-like
  • caspr1
  • contactin-associated protein 1
  • neurexin 4
  • neurexin IV
  • neurexin-4
  • p190
  • paranodin
  • MHDNIV
  • neurexin 4 (contactin associated protein)
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