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CLEC4A 产品

(C-Type Lectin Domain Family 4, Member A (CLEC4A))

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This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008].

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Featured CLEC4A Categories

CLEC4A 抗体

High quality antibodies with extensive validation data.

CLEC4A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CLEC4A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN7180295
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193222
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN3016507
Quantity 100 μL
Datasheet Datasheet

Recommended CLEC4A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730459
Quantity 96 tests
Datasheet Datasheet

Recommended CLEC4A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274354
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274364
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122063
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CLEC4A Products

Bloem, García-Vallejo, Vuist, Cobb, van Vliet, van Kooyk: "Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells." in: Frontiers in immunology, Vol. 4, pp. 103, (2013) (PubMed).

Bloem, Vuist, van der Plas, Knippels, Garssen, García-Vallejo, van Vliet, van Kooyk: "Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain." in: PLoS ONE, Vol. 8, Issue 6, pp. e66266, (2013) (PubMed).

Tel, Sittig, Blom, Cruz, Schreibelt, Figdor, de Vries: "Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 5005-12, (2013) (PubMed).

Tjomsland, Spångeus, Sandström, Borch, Messmer, Larsson: "Semi mature blood dendritic cells exist in patients with ductal pancreatic adenocarcinoma owing to inflammatory factors released from the tumor." in: PLoS ONE, Vol. 5, Issue 10, pp. e13441, (2010) (PubMed).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Meyer-Wentrup, Cambi, Joosten, Looman, de Vries, Figdor, Adema: "DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production." in: Journal of leukocyte biology, Vol. 85, Issue 3, pp. 518-25, (2009) (PubMed).

Meyer-Wentrup, Benitez-Ribas, Tacken, Punt, Figdor, de Vries, Adema: "Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production." in: Blood, Vol. 111, Issue 8, pp. 4245-53, (2008) (PubMed).

Synonyms and alternative names related to CLEC4A

zinc finger protein 705A (ZNF705A), C-type lectin domain family 4 member A (CLEC4A), C-type lectin domain family 4, member A (Clec4a), C-type lectin domain family 4, member a2 (Clec4a2), CLEC4A, Clec4a, CLECSF6, Clecsf6, DCIR, Dcir1, DDB27, LLIR

Protein level used designations for CLEC4A

  • C-type lectin domain family 4, member A
  • C-type lectin, superfamily member 6
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6
  • C-type lectin DDB27
  • C-type lectin domain family 4 member A
  • C-type lectin superfamily member 6
  • dendritic cell immunoreceptor
  • lectin-like immunoreceptor
  • C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6
  • dendritic cell inhibitory receptor 1
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