Claudin 16 产品
(Claudin 16 (CLDN16))
Categories
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. [provided by RefSeq, Jun 2010].
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Featured Claudin 16 Categories
Claudin 16 抗体
High quality antibodies with extensive validation data.
Claudin 16 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Claudin 16 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Claudin 16 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN524133
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN564659
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN654394
Quantity
400 μL
Datasheet
Datasheet
Recommended Claudin 16 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965845
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954822
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1742863
Quantity
96 tests
Datasheet
Datasheet
Recommended Claudin 16 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349597
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349596
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407367
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Claudin 16 Products
: "Claudin-19 and the barrier properties of the human retinal pigment epithelium." in: Investigative ophthalmology & visual science, Vol. 52, Issue 3, pp. 1392-403, (2011) (PubMed).: "MicroRNA-204/211 alters epithelial physiology." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 5, pp. 1552-71, (2010) (PubMed).
Synonyms and alternative names related to Claudin 16
claudin 16 (CLDN16), claudin 16 (Cldn16), claudin-16, CLDN16, HOMG3, PCLN1, Pcln1Protein level used designations for Claudin 16
- claudin 16
- PCLN-1
- claudin-16
- hypomagnesemia 3, with hypercalciuria and nephrocalcinosis
- paracellin-1
- CL-16
- H59D2a protein
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