CKAP5 产品
(Cytoskeleton Associated Protein 5 (CKAP5))
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This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation\; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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CKAP5 抗体
High quality antibodies with extensive validation data.
Recommended CKAP5 抗体
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Reactivity
Human
Application
WB, IP, IF
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- (5)
Cat. No.
ABIN6138647
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (4)
Cat. No.
ABIN7149368
Quantity
100 μg
Datasheet
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Human, Mouse, Rat
Application
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Validations
- (1)
Cat. No.
ABIN7264583
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Recommended CKAP5 蛋白
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Source
Escherichia coli (E. coli)
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ABIN7421719
Quantity
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Datasheet
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Latest Publications for our CKAP5 Products
: "In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215." in: Molecular biology of the cell, Vol. 29, Issue 11, pp. 1311-1317, (2018) (PubMed).: "PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 4, pp. 498-505, (2016) (PubMed).
: "ch-TOGp is required for microtubule aster formation in a mammalian mitotic extract." in: The Journal of biological chemistry, Vol. 275, Issue 16, pp. 12346-52, (2000) (PubMed).
Synonyms and alternative names related to CKAP5
cytoskeleton associated protein 5 (ckap5), cytoskeleton associated protein 5 S homeolog (ckap5.S), cytoskeleton associated protein 5 (CKAP5), cytoskeleton-associated protein 5 (LOC100548902), cytoskeleton associated protein 5 (Ckap5), 3110043H24Rik, 4930432B04Rik, ch-TOG, CHTOG, ckap5, CKAP5, ckap5b, D730027C18Rik, im:7143385, mKIAA0097, msps, MSPS, T25636, tog, TOG, togp, TOGp, wu:fb14c01, wu:fb59e03, wu:fi33f02, xmap215, zgc:123012Protein level used designations for CKAP5
- cytoskeleton associated protein 5
- microtubule associated protein XMAP215
- cytoskeleton-associated protein 5
- microtubule-associated protein 215
- colonic and hepatic tumor over-expressed protein
- Cytoskeleton-associated protein 5
- cytoskeleton-associated protein 5-like
- colonic and hepatic tumor over-expressed gene protein
- colonic and hepatic tumor overexpressed gene protein
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