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CIT 产品

(Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

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This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].

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Featured CIT Categories

CIT 抗体

High quality antibodies with extensive validation data.

CIT 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CIT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7183401
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN564821
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1679238
Quantity 100 μg
Datasheet Datasheet

Recommended CIT ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6213951
Quantity 96 tests
Datasheet Datasheet

Recommended CIT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349513
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509159
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623968
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CIT Products

Hosono, Yamaguchi, Mizutani, Yanagisawa, Arima, Tomida, Shimada, Hiraoka, Kato, Yokoi, Suzuki, Takahashi: "MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis." in: The EMBO journal, Vol. 31, Issue 2, pp. 481-93, (2012) (PubMed).

Liu, Di Cunto, Imarisio, Reid: "Citron kinase is a cell cycle-dependent, nuclear protein required for G2/M transition of hepatocytes." in: The Journal of biological chemistry, Vol. 278, Issue 4, pp. 2541-8, (2003) (PubMed).

Furuyashiki, Fujisawa, Fujita, Madaule, Uchino, Mishina, Bito, Narumiya: "Citron, a Rho-target, interacts with PSD-95/SAP-90 at glutamatergic synapses in the thalamus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 1, pp. 109-18, (1999) (PubMed).

Zhang, Vazquez, Apperson, Kennedy: "Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 1, pp. 96-108, (1999) (PubMed).

Di Cunto, Calautti, Hsiao, Ong, Topley, Turco, Dotto: "Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron." in: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29706-11, (1998) (PubMed).

Madaule, Eda, Watanabe, Fujisawa, Matsuoka, Bito, Ishizaki, Narumiya: "Role of citron kinase as a target of the small GTPase Rho in cytokinesis." in: Nature, Vol. 394, Issue 6692, pp. 491-4, (1998) (PubMed).

Synonyms and alternative names related to CIT

citron rho-interacting serine/threonine kinase (Cit), citron rho-interacting serine/threonine kinase (CIT), citron (rho-interacting, serine/threonine kinase 21) (CIT), citron Rho-interacting kinase (LOC100083347), citron rho-interacting serine/threonine kinase (cit), citron (Cit), C030025P15Rik, CIT, Cit-k, crik, CRIK, CRIK-SK, stk21, STK21, xcit

Protein level used designations for CIT

  • citron Rho-interacting kinase
  • citron kinase
  • citron-K kinase
  • postsynaptic density protein (citron)
  • citron (rho-interacting, serine/threonine kinase 21)
  • citron-N
  • rho-interacting, serine/threonine-protein kinase 21
  • serine/threonine-protein kinase 21
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