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CHRNA7 蛋白

(Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

recommended

CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) (ABIN7122359)

CHRNA7 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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CHRNA7 Protein (GST tag) (ABIN7508493)

CHRNA7 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

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recommended

CHRNA7 Protein (AA 23-230) (His tag,GST tag) (ABIN7413079)

CHRNA7 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % WB, PC, Imm, SDS

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CHRNA7 蛋白 by Origin

Find CHRNA7 蛋白 for a variety of species such as anti-Human CHRNA7, anti-Rat CHRNA7. The species listed below are among those available. Click on a link to go to the corresponding products.

CHRNA7 蛋白 by Source

Here you will find CHRNA7 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CHRNA7 蛋白 by 蛋白类型

Here you can find CHRNA7 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CHRNA7 蛋白 by 应用范围

Find CHRNA7 蛋白 validated for a specific application such as WB, PC, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CHRNA7 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CHRNA7 Protein (AA 25-129) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7122359

Quantity 50 μg

Datasheet Datasheet

CHRNA7 Protein (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN7508493

Quantity 10 μg

Datasheet Datasheet

CHRNA7 Protein (AA 23-230) (His tag,GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7413079

Quantity 100 μg

Datasheet Datasheet

CHRNA7 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7424392

Quantity 100 μg

Datasheet Datasheet

CHRNA7 蛋白

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2750643

Quantity 5 applications

Datasheet Datasheet

Latest Publications for our CHRNA7 蛋白

Chandley, Miller, Kwasigroch, Wilson, Miller: "Increased antibodies for the alpha7 subunit of the nicotinic receptor in schizophrenia." in: Schizophrenia research, Vol. 109, Issue 1-3, pp. 98-101, (2009) (PubMed).

Aliases for CHRNA7 蛋白

cholinergic receptor nicotinic alpha 7 subunit (CHRNA7) 蛋白
neuronal acetylcholine receptor subunit alpha-7 (LOC100374356) 蛋白
cholinergic receptor, nicotinic, alpha 7 (neuronal) (chrna7) 蛋白
cholinergic receptor, nicotinic, alpha polypeptide 7 (Chrna7) 蛋白
cholinergic receptor nicotinic alpha 7 subunit (Chrna7) 蛋白
cholinergic receptor, nicotinic, alpha 7 (CHRNA7) 蛋白
neuronal acetylcholine receptor subunit alpha-7 (LOC100060521) 蛋白
Acra7 蛋白
alpha7 蛋白
BTX 蛋白
CHRNA7 蛋白
CHRNA7-2 蛋白
dZ70B1.1 蛋白
NACHRA7 蛋白
nAChRa7 蛋白
NARAD 蛋白

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CHRNA7 蛋白 by Origin

CHRNA7 蛋白 by Source

CHRNA7 蛋白 by 蛋白类型

CHRNA7 蛋白 by 应用范围

Popular CHRNA7 蛋白

Latest Publications for our CHRNA7 蛋白

Aliases for CHRNA7 蛋白

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