CHN2 产品
(Chimerin (Chimaerin) 2 (CHN2))
Categories
This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured CHN2 Categories
Recommended CHN2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7444778
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN5013327
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7145458
Quantity
100 μg
Datasheet
Datasheet
Recommended CHN2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6215198
Quantity
96 tests
Datasheet
Datasheet
Recommended CHN2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418860
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418863
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418866
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CHN2 Products
: "Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility." in: Oncotarget, Vol. 6, Issue 25, pp. 20863-74, (2015) (PubMed).: "T cell receptor-dependent tyrosine phosphorylation of beta2-chimaerin modulates its Rac-GAP function in T cells." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11354-63, (2009) (PubMed).
Synonyms and alternative names related to CHN2
chimerin 2 (chn2), chimerin 2 (CHN2), chimerin 2 (Chn2), chimerin 2 L homeolog (chn2.L), 1700026N20Rik, 4930557O16Rik, ARHGAP3, Bch, BCH, CHN2-3, RHOGAP3Protein level used designations for CHN2
- beta chimerin
- chimerin (chimaerin) 2
- beta-chimaerin-like
- beta-chimaerin
- Rho GTPase-activating protein 3
- beta chimaerin
- beta-chimerin
- beta3-chimaerin
- chimaerin 2
- rho-GTPase-activating protein 3
- rho GTPase-activating protein 3
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- Cholesterol Oxidase
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- Choline Acetyltransferase
- Choline Kinase alpha
- Choline Oxidase
- Cholylglycine
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- Chondroitin Sulfate Proteoglycan
- CHORDC1
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- Chorionic Gonadotropin
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