CHMP4B 产品
(Charged Multivesicular Body Protein 4B (CHMP4B))
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This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009].
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Featured CHMP4B Categories
Recommended CHMP4B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (4)
Cat. No.
ABIN872575
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6138549
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (3)
Cat. No.
ABIN7011771
Quantity
60 μL
Datasheet
Datasheet
Recommended CHMP4B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228058
Quantity
96 tests
Datasheet
Datasheet
Recommended CHMP4B 蛋白
Latest Publications for our CHMP4B Products
: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." in: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).: "Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane." in: The Journal of biological chemistry, Vol. 286, Issue 46, pp. 40276-86, (2011) (PubMed).
Synonyms and alternative names related to CHMP4B
charged multivesicular body protein 4B (CHMP4B), charged multivesicular body protein 4B (Chmp4b), charged multivesicular body protein 4Ba (chmp4ba), charged multivesicular body protein 4B L homeolog (chmp4b.L), charged multivesicular body protein 4Bb (chmp4bb), 2010012F05Rik, C20orf178, c20orf178, C76846, CHMP4A, CHMP4b, chmp4b, chmp4b.S, CHMP4c, CTPP3, CTRCT31, dJ553F4.4, RGD1309846, RGD1565889, Shax1, SNF7, SNF7-2, Snf7-2, Vps32-2, VPS32B, wu:fc96b02, zgc:55566Protein level used designations for CHMP4B
- SNF7 homolog associated with Alix 1
- Snf7 homologue associated with Alix 1
- charged multivesicular body protein 4b
- chromatin modifying protein 4B
- chromatin-modifying protein 4b
- hSnf7-2
- hVps32-2
- vacuolar protein sorting-associated protein 32-2
- vacuolar protein-sorting-associated protein 32-2
- CHMP4b
- Chromatin-modifying protein 4b
- charged multivesicular body protein 4B S homeolog
- CHMP4c
- Chromatin-modifying protein 4c
- charged multivesicular body protein 4B
- charged multivesicular body protein 4c
- chromatin-modifying protein 4c
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