Chloride Channel 5 产品
(Chloride Channel 5 (CLCN5))
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This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013].
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Chloride Channel 5 抗体
High quality antibodies with extensive validation data.
Chloride Channel 5 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Chloride Channel 5 抗体
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Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (3)
Cat. No.
ABIN7073471
Quantity
100 μL
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Datasheet
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Human
Application
WB
Validations
- (4)
- (1)
Cat. No.
ABIN1881207
Quantity
400 μL
Datasheet
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Recommended Chloride Channel 5 蛋白
Latest Publications for our Chloride Channel 5 Products
: "The interaction between megalin and ClC-5 is scaffolded by the Na?-H? exchanger regulatory factor 2 (NHERF2) in proximal tubule cells." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 5, pp. 815-23, (2012) (PubMed).: "Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies." in: PLoS ONE, Vol. 7, Issue 9, pp. e45605, (2012) (PubMed).
: "Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3696-705, (2010) (PubMed).
: "ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 2, pp. 543-57, (2010) (PubMed).
: "Proton block of the CLC-5 Cl-/H+ exchanger." in: The Journal of general physiology, Vol. 135, Issue 6, pp. 653-9, (2010) (PubMed).
: "On the position and value of those Lesions of the Brain which cause a rise of Temperature." in: The Journal of physiology, Vol. 12, Issue 3, pp. 233-298.3, (2007) (PubMed).
: "Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients." in: Kidney international, Vol. 63, Issue 4, pp. 1285-95, (2003) (PubMed).
: "De novo insertion of an Alu sequence in the coding region of the CLCN5 gene results in Dent's disease." in: Human genetics, Vol. 113, Issue 6, pp. 480-5, (2003) (PubMed).
: "Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5." in: Kidney international, Vol. 65, Issue 1, pp. 198-208, (2003) (PubMed).
Synonyms and alternative names related to Chloride Channel 5
chloride voltage-gated channel 5 (CLCN5), chloride channel, voltage-sensitive 5 L homeolog (clcn5.L), chloride channel, voltage-sensitive 5 (clcn5), chloride channel, voltage-sensitive 5 (Clcn5), chloride voltage-gated channel 5 (Clcn5), 5430408K11Rik, ClC-5, Clc5, CLC5, CLCK2, CLCN3, CLCN4, CLCN5, Clcn5, clcn5-A, D930009B12Rik, DENTS, DKFZp469O2315, DXImx42e, hCIC-K2, NPHL1, NPHL2, Sfc13, T25545, XLRH, XRNProtein level used designations for Chloride Channel 5
- chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease)
- chloride channel protein 5
- chloride channel 5
- H(+)/Cl(-) exchange transporter 5-like
- Chloride channel protein 5
- H(+)/Cl(-) exchange transporter 5
- chloride transporter ClC-5
- voltage-gated chloride ion channel CLCN5
- clC-5
- chloride channel CLC-5
- chloride channel CLCN5
- chloride channel Clc-5
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