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CHEK2 ELISA试剂盒

(Checkpoint Kinase 2 (CHEK2))
In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
CHEK2 ELISA 试剂盒 (ABIN1380543)

CHEK2 适用: 人 pSer516 Colorimetric Cell ELISA Cell Culture Cells

CHEK2 ELISA 试剂盒 (ABIN1380343)

CHEK2 适用: 人, 小鼠, 大鼠 pThr383 Colorimetric Cell ELISA Cell Culture Cells

CHEK2 ELISA 试剂盒 (ABIN1380544)

CHEK2 适用: 人, 小鼠, 大鼠 pThr68 Colorimetric Cell ELISA Cell Culture Cells

CHEK2 ELISA试剂盒 by 适用

Find CHEK2 ELISA试剂盒 for a variety of species such as anti-Human CHEK2, anti-Mouse CHEK2, anti-Rat CHEK2. The species listed below are among those available. Click on a link to go to the corresponding products.

CHEK2 ELISA试剂盒 by 检测方法

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CHEK2 ELISA试剂盒 by Analytical Method

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CHEK2 ELISA试剂盒 by 样本

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CHEK2 ELISA试剂盒 by 抗原表位

Find CHEK2 ELISA试剂盒 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Popular CHEK2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380543
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380343
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380544
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380161
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886026
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886029
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6230861
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6230860
Quantity 96 tests
Datasheet Datasheet

Aliases for CHEK2 ELISA试剂盒

checkpoint kinase 2 (CHEK2) ELISA试剂盒
checkpoint kinase 2 (chek2) ELISA试剂盒
checkpoint kinase 2 (Chek2) ELISA试剂盒
serine/threonine-protein kinase chk2 (MCYG_07308) ELISA试剂盒
checkpoint kinase 2 L homeolog (chek2.L) ELISA试剂盒
CDS1 ELISA试剂盒
Cds1 ELISA试剂盒
cds1 ELISA试剂盒
chek2 ELISA试剂盒
CHK2 ELISA试剂盒
Chk2 ELISA试剂盒
chk2 ELISA试剂盒
fa66f08 ELISA试剂盒
hCds1 ELISA试剂盒
HuCds1 ELISA试剂盒
HUCDS1 ELISA试剂盒
hucds1 ELISA试剂盒
LFS2 ELISA试剂盒
lfs2 ELISA试剂盒
PP1425 ELISA试剂盒
pp1425 ELISA试剂盒
RAD53 ELISA试剂盒
Rad53 ELISA试剂盒
rad53 ELISA试剂盒
wu:fa66f08 ELISA试剂盒
zgc:55865 ELISA试剂盒
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