CHD4 产品
(Chromodomain Helicase DNA Binding Protein 4 (CHD4))
Categories
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq, Jul 2008].
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Featured CHD4 Categories
CHD4 抗体
High quality antibodies with extensive validation data.
CHD4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CHD4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CHD4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7255670
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (2)
- (5)
Cat. No.
ABIN560357
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6138512
Quantity
100 μL
Datasheet
Datasheet
Recommended CHD4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954775
Quantity
96 tests
Datasheet
Datasheet
Recommended CHD4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349294
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397285
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7403291
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CHD4 Products
: "Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA." in: Experimental dermatology, (2023) (PubMed).: "Distinct Requirements of CHD4 during B Cell Development and Antibody Response." in: Cell reports, Vol. 27, Issue 5, pp. 1472-1486.e5, (2019) (PubMed).
: "CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity." in: The Journal of clinical investigation, Vol. 126, Issue 6, pp. 2254-66, (2016) (PubMed).
: "Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex." in: The Journal of biological chemistry, Vol. 289, Issue 42, pp. 28956-70, (2014) (PubMed).
: "Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14881-95, (2014) (PubMed).
: "The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis." in: PLoS genetics, Vol. 9, Issue 12, pp. e1004031, (2013) (PubMed).
: "The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling." in: Molecular and cellular biology, Vol. 32, Issue 7, pp. 1312-20, (2012) (PubMed).
: "Sin3a is essential for the genome integrity and viability of pluripotent cells." in: Developmental biology, Vol. 363, Issue 1, pp. 62-73, (2012) (PubMed).
: "Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 450-9, (2011) (PubMed).
: "Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development." in: Biology of reproduction, Vol. 83, Issue 6, pp. 1027-35, (2010) (PubMed).
Synonyms and alternative names related to CHD4
chromodomain helicase DNA binding protein 4 (CHD4), chromodomain helicase DNA binding protein 4a (chd4a), chromodomain helicase DNA binding protein 4b (chd4b), chromodomain helicase DNA binding protein 4 (chd4), chromodomain helicase DNA binding protein 4 (Chd4), chromodomain helicase DNA binding protein 4 L homeolog (chd4.L), 9530019N15Rik, AA617397, b230399n07, BC005710, CHD4, D6Ertd380e, im:7143343, MGC145363, Mi-2, Mi-2b, Mi-2beta, Mi2-BETA, mKIAA4075, si:ch211-51m24.3, si:ch211-57k11.10, wu:fb44b12, wu:fd12d03Protein level used designations for CHD4
- chromodomain helicase DNA binding protein 4
- chromodomain-helicase-DNA-binding protein 4
- ATP-dependent helicase CHD4
- CHD-4
- Mi-2 autoantigen 218 kDa protein
- Mi-2 autoantigen
- Mi-2 beta
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