CFTR 产品
(Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
Categories
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008].
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Featured CFTR Categories
CFTR 抗体
High quality antibodies with extensive validation data.
CFTR ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CFTR 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CFTR 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (3)
Cat. No.
ABIN7434899
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (f), FACS
Validations
- (3)
Cat. No.
ABIN6939092
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IF, WB
Validations
- (3)
Cat. No.
ABIN6138469
Quantity
100 μL
Datasheet
Datasheet
Recommended CFTR ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966205
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962401
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955205
Quantity
96 tests
Datasheet
Datasheet
Recommended CFTR 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349232
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396334
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3112877
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CFTR Products
: "β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis." in: The American journal of pathology, Vol. 189, Issue 4, pp. 813-825, (2019) (PubMed).: "Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis." in: Nature medicine, Vol. 23, Issue 5, pp. 590-600, (2017) (PubMed).
: "High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo." in: Oncology reports, Vol. 33, Issue 5, pp. 2227-34, (2015) (PubMed).
: "Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 11, pp. 2939-48, (2007) (PubMed).
: "CFTR regulates phagosome acidification in macrophages and alters bactericidal activity." in: Nature cell biology, Vol. 8, Issue 9, pp. 933-44, (2006) (PubMed).
: "Acceleration of glutathione efflux and inhibition of gamma-glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6950-9, (2005) (PubMed).
: "Differential regulation of cystic fibrosis transmembrane conductance regulator by interferon gamma in mast cells and epithelial cells." in: The Journal of pharmacology and experimental therapeutics, Vol. 315, Issue 2, pp. 563-70, (2005) (PubMed).
: "PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture." in: American journal of physiology. Renal physiology, Vol. 284, Issue 5, pp. F987-95, (2003) (PubMed).
: "Polarization of specific tropomyosin isoforms in gastrointestinal epithelial cells and their impact on CFTR at the apical surface." in: Molecular biology of the cell, Vol. 14, Issue 11, pp. 4365-75, (2003) (PubMed).
: "Expression and functional characterization of CFTR in mast cells." in: Journal of leukocyte biology, Vol. 71, Issue 1, pp. 54-64, (2002) (PubMed).
Synonyms and alternative names related to CFTR
cystic fibrosis transmembrane conductance regulator (CFTR), cystic fibrosis transmembrane conductance regulator (cftr-A), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (CFTR), cystic fibrosis transmembrane conductance regulator (Cftr), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (cftr), ABC35, abc35, ABCC7, Abcc7, abcc7, AW495489, CF, CFTR, CFTR/MRP, cftr/mrp, dJ760C5.1, MRP7, mrp7, RGD1561193, si:dkey-270i2.2, TNR-CFTR, tnr-cftr, xcftrProtein level used designations for CFTR
- cAMP-dependent chloride channel
- channel conductance-controlling ATPase
- cystic fibrosis transmembrane conductance regulator
- cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
- ATP-binding cassette sub-family C member 7
- ATP-binding cassette transporter sub-family C member 7
- ATP-binding cassette, subfamily c, member 7
- cystic fibrosis transmembrane conductance regulator homolog
- cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7
- CFTR chloride channel
- chloride channel
- CFTR cAMP-dependent chloride channel protein
- Channel conductance-controlling ATPase
- abcc7
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