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CFLA 抗体 (Center)

VVL 适用: 人 FACS, IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2793618
发货至: 中国
  • 抗原
    CFLA (VVL) (POU Domain Protein CF1A (VVL))
    抗原表位
    AA 145-174, Center
    适用
    宿主
    克隆类型
    多克隆
    应用范围
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
    原理
    Rabbit Anti-Human CFLAR (Center) Antibody
    免疫原
    This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.
    亚型
    Ig Fraction
  • 应用备注
    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of CFLAR Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.000 mg/mL
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    CFLA (VVL) (POU Domain Protein CF1A (VVL))
    别名
    CFLA
    背景

    Target Description: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.

    Gene Symbol: CFLAR

    分子量
    55344 Da
    基因ID
    8837
    UniProt
    O15519
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