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CENPF 产品

(Centromere Protein F (CENPF))

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This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008].

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Featured CENPF Categories

CENPF 抗体

High quality antibodies with extensive validation data.

CENPF ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended CENPF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC, IHC (wm)
Validations
  • (1)
  • (3)
Cat. No. ABIN2854654
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7431644
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN6260754
Quantity 100 μL
Datasheet Datasheet

Recommended CENPF ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965627
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954556
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1742813
Quantity 96 tests
Datasheet Datasheet

Recommended CENPF 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349108
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390121
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CENPF Products

Yamauchi, Shibata, Suzuki, Suzuki, Niimi, Kondo, Miura, Hirakawa, Tsujita, Yamashita, Matsuda: "Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1." in: Scientific reports, Vol. 7, pp. 41812, (2018) (PubMed).

Chong, Sarac, Yao, Liao, Lyttle, Boutros, Bartlett, Spears: "Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer." in: Journal of ovarian research, Vol. 11, Issue 1, pp. 27, (2018) (PubMed).

Ciossani, Overlack, Petrovic, Huis In t Veld, Koerner, Wohlgemuth, Maffini, Musacchio: "The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases." in: The Journal of biological chemistry, Vol. 293, Issue 26, pp. 10084-10101, (2018) (PubMed).

Sikirzhytski, Renda, Tikhonenko, Magidson, McEwen, Khodjakov: "Microtubules assemble near most kinetochores during early prometaphase in human cells." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2647-2659, (2018) (PubMed).

Rodriguez-Rodriguez, Lewis, McKinley, Sikirzhytski, Corona, Maciejowski, Khodjakov, Cheeseman, Jallepalli: "Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion." in: Current biology : CB, Vol. 28, Issue 21, pp. 3422-3429.e5, (2018) (PubMed).

Magidson, He, Ault, OConnell, Yang, Tikhonenko, McEwen, Sui, Khodjakov: "Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells." in: The Journal of cell biology, Vol. 212, Issue 3, pp. 307-19, (2016) (PubMed).

Ma, Hou, Zhang, Sun, Schedl, Moley, Wang: "Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 9, pp. 4026-35, (2015) (PubMed).

Lee, Lee, Lee: "CaMKKβ-AMPKα2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 4, pp. 598-611, (2015) (PubMed).

Nakajima, Hagiwara, Oike, Okayasu, Murakami, Nakano, Shibata: "Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repair." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122582, (2015) (PubMed).

Bee, Nasca, Zanolini, Cendron, dAdamo, Costa, Lamperti, Celotti, Ghezzi, Zeviani: "A nonsense mutation of human XRCC4 is associated with adult-onset progressive encephalocardiomyopathy." in: EMBO molecular medicine, Vol. 7, Issue 7, pp. 918-29, (2015) (PubMed).

Synonyms and alternative names related to CENPF

centromere protein F (CENPF), centromere protein F (Cenpf), centromere protein F (cenpf), 6530404A22Rik, AI325968, CENF, CMF1, hcp-1, im:7140452, im:7144238, im:7154719, im:7156761, Lek1, LOC100222985, mitosin, PRO1779, si:ch211-152h14.2

Protein level used designations for CENPF

  • centromere protein F
  • centromere autoantigen F
  • leucine, glutamic acid, lysine family 1 protein
  • LEK/centromere protein
  • AH antigen
  • CENP-F kinetochore protein
  • cell-cycle-dependent 350K nuclear protein
  • centromere protein F, 350/400kDa (mitosin)
  • centromere protein F, 350/400ka (mitosin)
  • kinetochore protein CENPF
  • mitosin
  • cardiac muscle factor 1 CMF1
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