CELF1 产品
(CUGBP, Elav-Like Family Member 1 (CELF1))
Categories
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured CELF1 Categories
CELF1 抗体
High quality antibodies with extensive validation data.
CELF1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CELF1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CELF1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP
Validations
- (5)
Cat. No.
ABIN6138399
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN948978
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN524102
Quantity
100 μg
Datasheet
Datasheet
Recommended CELF1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1773938
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743034
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1744255
Quantity
96 tests
Datasheet
Datasheet
Recommended CELF1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1350750
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091407
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133586
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CELF1 Products
: "Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal." in: Molecular biology of the cell, Vol. 26, Issue 10, pp. 1797-810, (2015) (PubMed).: "Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1." in: American journal of physiology. Cell physiology, Vol. 306, Issue 12, pp. C1167-75, (2014) (PubMed).
: "Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function." in: Molecular biology of the cell, Vol. 24, Issue 2, pp. 85-99, (2013) (PubMed).
: "Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy." in: PLoS genetics, Vol. 9, Issue 4, pp. e1003445, (2013) (PubMed).
: "Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 39, pp. 13587-96, (2012) (PubMed).
: "Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines." in: Molecular biology of the cell, Vol. 22, Issue 17, pp. 3055-69, (2011) (PubMed).
: "CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1." in: Human molecular genetics, Vol. 19, Issue 18, pp. 3614-22, (2010) (PubMed).
: "Ectopic expression of CGG containing mRNA is neurotoxic in mammals." in: Human molecular genetics, Vol. 18, Issue 13, pp. 2443-51, (2009) (PubMed).
: "Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2646-51, (2008) (PubMed).
: "Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice." in: Molecular and cellular biology, Vol. 27, Issue 3, pp. 1146-57, (2007) (PubMed).
Synonyms and alternative names related to CELF1
CUGBP Elav-like family member 1 (CELF1), CUGBP, Elav-like family member 1 (Celf1), cugbp, Elav-like family member 1 (celf1), CUGBP, Elav-like family member 1 (CELF1), CUGBP Elav-like family member 1 L homeolog (celf1.L), CUGBP Elav-like family member 1 (Celf1), 1600010O03Rik, AA407467, brul, Bruno-like, BRUNOL2, Brunol2, brunol2, cb920, CUG-BP, cug-bp, CUG-BP1, cug-bp1, CUGBP, cugbp, CUGBP1, Cugbp1, cugbp1, cugbp1-a, D2Wsu101e, EDEN-BP, eden-bp, edenbp, hNab50, HNAB50, NAB50, nab50, NAPORProtein level used designations for CELF1
- CUG triplet repeat, RNA binding protein 1
- CUGBP Elav-like family member 1
- 50 kDa nuclear polyadenylated RNA-binding protein
- CELF-1
- CUG RNA-binding protein
- CUG triplet repeat RNA-binding protein 1
- CUG triplet repeat, RNA-binding protein 1
- CUG-BP- and ETR-3-like factor 1
- CUG-BP1
- EDEN-BP homolog
- RNA-binding protein BRUNOL-2
- bruno-like 2
- bruno-like protein 2
- deadenylation factor CUG-BP
- embryo deadenylation element binding protein
- embryo deadenylation element-binding protein homolog
- nuclear polyadenylated RNA-binding protein, 50-kD
- brain protein F41
- deadenylation factor EDEN-BP
- EDEN-BP/Bruno-like protein
- CELF-1A
- CUG triplet repeat RNA-binding protein 1-A
- CUG-BP- and ETR-3-like factor 1-A
- CUG-BP1-A
- CUGBP Elav-like family member 1-A
- EDEN-BP-A
- RNA-binding protein BRUNOL-2-A
- bruno-like protein 2-A
- embryo deadenylation element-binding protein A
- p53/p55
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