Integrin AlphaV, Integrin Beta3 产品
(Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009].
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Featured Integrin AlphaV, Integrin Beta3 Categories
Integrin AlphaV, Integrin Beta3 抗体
High quality antibodies with extensive validation data.
Integrin AlphaV, Integrin Beta3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Integrin AlphaV, Integrin Beta3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS, WB, IF (cc), IF (p), IHC (fro), ELISA, IHC (p)
Validations
- (10)
- (2)
Cat. No.
ABIN674784
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, IHC
Validations
- (3)
- (1)
Cat. No.
ABIN2191903
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Human, Rabbit
Application
FACS, IHC, IHC (fro)
Validations
- (1)
Cat. No.
ABIN205432
Quantity
100 μg
Datasheet
Datasheet
Recommended Integrin AlphaV, Integrin Beta3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968072
Quantity
96 tests
Datasheet
Datasheet
Recommended Integrin AlphaV, Integrin Beta3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275059
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275055
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275060
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Integrin AlphaV, Integrin Beta3 Products
: "Radioiodinated bicyclic RGD peptide for imaging integrin αvβ3 in cancers." in: Biochemical and biophysical research communications, Vol. 528, Issue 1, pp. 168-173, (2021) (PubMed).: "GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer." in: Theranostics, Vol. 9, Issue 4, pp. 1047-1065, (2019) (PubMed).
: "The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model." in: Journal of cellular and molecular medicine, Vol. 23, Issue 8, pp. 5176-5192, (2019) (PubMed).
: "The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation." in: Nature communications, Vol. 10, Issue 1, pp. 3181, (2019) (PubMed).
: "cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 261, pp. 275-286, (2018) (PubMed).
: "Osteopontin-integrin engagement induces HIF-1α-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer." in: Oncotarget, Vol. 9, Issue 4, pp. 4998-5015, (2018) (PubMed).
: "HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 7, pp. 2372-2390, (2018) (PubMed).
: "Evaluation of a dimeric-cRGD peptide for targeted PET-CT imaging of peripheral angiogenesis in diabetic mice." in: Scientific reports, Vol. 8, Issue 1, pp. 5401, (2018) (PubMed).
: "Acidic preconditioning of endothelial colony-forming cells (ECFC) promote vasculogenesis under proinflammatory and high glucose conditions in vitro and in vivo." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 120, (2018) (PubMed).
: "Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis." in: Bone research, Vol. 5, pp. 17008, (2017) (PubMed).
Synonyms and alternative names related to Integrin AlphaV, Integrin Beta3
integrin subunit alpha V (ITGAV), CD51, MSK8, VNRA, VTNRProtein level used designations for Integrin AlphaV, Integrin Beta3
- antigen identified by monoclonal antibody L230
- integrin alpha-V
- integrin alphaVbeta3
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- vitronectin receptor subunit alpha
- vitronectin receptor alpha subunit
- integrin alpha V subunit
- alphaV integrin
- integrin alpha v
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