电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CDT2/RAMP 蛋白

(Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis (By similarity).
CDT2/RAMP Protein (AA 1-730) (Strep Tag) (ABIN3092255)

DTL 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

CDT2/RAMP Protein (AA 1-729) (Strep Tag) (ABIN3134980)

DTL 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

CDT2/RAMP Protein (GST tag,His tag) CDT2/RAMP Protein (GST tag,His tag) CDT2/RAMP Protein (GST tag,His tag) (ABIN5505614)

DTL 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP

CDT2/RAMP 蛋白 by Origin

Find CDT2/RAMP 蛋白 for a variety of species such as anti-Human CDT2/RAMP, anti-Mouse CDT2/RAMP. The species listed below are among those available. Click on a link to go to the corresponding products.

CDT2/RAMP 蛋白 by Source

Here you will find CDT2/RAMP 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CDT2/RAMP 蛋白 by 蛋白类型

Here you can find CDT2/RAMP 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CDT2/RAMP 蛋白 by 应用范围

Find CDT2/RAMP 蛋白 validated for a specific application such as ELISA, SDS, WB, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CDT2/RAMP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092255
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134980
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5505614
Quantity 50 μg
Datasheet Datasheet

Aliases for CDT2/RAMP 蛋白

denticleless E3 ubiquitin protein ligase homolog (DTL) 蛋白
denticleless E3 ubiquitin protein ligase (Dtl) 蛋白
denticleless E3 ubiquitin protein ligase homolog (Dtl) 蛋白
denticleless E3 ubiquitin protein ligase homolog S homeolog (dtl.S) 蛋白
denticleless E3 ubiquitin protein ligase homolog (Drosophila) (dtl) 蛋白
2810047L02Rik 蛋白
5730564G15Rik 蛋白
cb151 蛋白
CDT2 蛋白
cdt2 蛋白
cdt2-a 蛋白
chunp6871 蛋白
DCAF2 蛋白
dcaf2 蛋白
L2DTL 蛋白
l2dtl 蛋白
RAMP 蛋白
Ramp 蛋白
ramp 蛋白
RGD1310439 蛋白
wu:fb54b02 蛋白
You are here:
客服