CDKN2C 产品
(Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
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The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008].
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Featured CDKN2C Categories
CDKN2C 抗体
High quality antibodies with extensive validation data.
CDKN2C ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CDKN2C 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDKN2C 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7260089
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN947693
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7148889
Quantity
100 μg
Datasheet
Datasheet
Recommended CDKN2C ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966181
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN585376
Quantity
96 tests
Datasheet
Datasheet
Recommended CDKN2C 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122542
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349022
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7318364
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CDKN2C Products
: "Key roles for MYC, KIT and RET signaling in secondary angiosarcomas." in: British journal of cancer, Vol. 111, Issue 2, pp. 407-12, (2014) (PubMed).: "Contrasting behavior of the p18INK4c and p16INK4a tumor suppressors in both replicative and oncogene-induced senescence." in: Cancer research, Vol. 72, Issue 1, pp. 165-75, (2012) (PubMed).
Synonyms and alternative names related to CDKN2C
cyclin dependent kinase inhibitor 2C (CDKN2C), cyclin-dependent kinase inhibitor 2C (cdkn2c), cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (Cdkn2c), cyclin-dependent kinase inhibitor 2C (Cdkn2c), C77269, CDKN2C, ink4c, INK4C, INK4c, INK4d, p18, p18-ink4c, p18-INK4C, p18INK4cProtein level used designations for CDKN2C
- cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
- cyclin-dependent kinase 4 inhibitor C
- CDK6 inhibitor p18
- cyclin-dependent inhibitor
- cyclin-dependent kinase 6 inhibitor p18
- p18-INK6
- cyclin-dependent kinase 6 inhibitor
- p18-INK4c
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