CDK8 抗体
(Cyclin-Dependent Kinase 8 (CDK8))
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
CDK8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
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Find available monoclonal or polyclonal CDK8 抗体. Click on a link to go to the corresponding products.
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Popular CDK8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IP
Validations
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Cat. No.
ABIN6138329
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, ICC, IF
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Cat. No.
ABIN6257696
Quantity
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Datasheet
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Application
WB, ChIP-seq, ChIP
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Cat. No.
ABIN6971509
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p), IF (p)
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Cat. No.
ABIN670266
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
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Cat. No.
ABIN7188619
Quantity
100 μg
Datasheet
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Reactivity
Human
Application
WB, IHC, IP, ICC
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
ABIN6242788
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
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Cat. No.
ABIN3183844
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
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Validations
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Cat. No.
ABIN202585
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN391759
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN655911
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IP
Validations
Cat. No.
ABIN6989759
Quantity
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Datasheet
Datasheet
Latest Publications for our CDK8 抗体
: "Downregulation of cyclin-dependent kinase 8 by microRNA-148a suppresses proliferation and invasiveness of papillary thyroid carcinomas." in: American journal of cancer research, Vol. 7, Issue 10, pp. 2081-2090, (2018) (PubMed).: "MicroRNA-101 is a potential prognostic indicator of laryngeal squamous cell carcinoma and modulates CDK8." in: Journal of translational medicine, Vol. 13, pp. 271, (2015) (PubMed).
: "Human cyclin C protein is stabilized by its associated kinase cdk8, independently of its catalytic activity." in: Oncogene, Vol. 20, Issue 5, pp. 551-62, (2001) (PubMed).
: "Genomics of the human genes encoding four TAFII subunits of TFIID, the three subunits of TFIIA, as well as CDK8 and SURB7." in: Somatic cell and molecular genetics, Vol. 25, Issue 3, pp. 185-9, (2001) (PubMed).
: "TFIIH is negatively regulated by cdk8-containing mediator complexes." in: Nature, Vol. 407, Issue 6800, pp. 102-6, (2000) (PubMed).
: "Cyclins and cell cycle checkpoints." in: Annual review of pharmacology and toxicology, Vol. 39, pp. 295-312, (1999) (PubMed).
: "Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases." in: Oncogene, Vol. 18, Issue 4, pp. 1093-102, (1999) (PubMed).
Aliases for CDK8 抗体
cyclin dependent kinase 8 (CDK8) 抗体cyclin-dependent kinase 8 (Cdk8) 抗体
cyclin-dependent kinase 8 (cdk8) 抗体
cyclin-dependent kinase 8 S homeolog (cdk8.S) 抗体
Cyclin-dependent kinase 8 (cdk-8) 抗体
cyclin-dependent kinase 8 (CDK8) 抗体
cyclin dependent kinase 19 (CDK19) 抗体
K35 抗体
wu:fk95h11 抗体
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