CDK5RAP2 产品
(CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
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This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
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CDK5RAP2 抗体
High quality antibodies with extensive validation data.
Recommended CDK5RAP2 抗体
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Reactivity
Human
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ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7147230
Quantity
100 μg
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WB
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- (1)
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ABIN7266236
Quantity
100 μL
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ELISA, IHC
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ABIN7188618
Quantity
100 μg
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Recommended CDK5RAP2 蛋白
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Latest Publications for our CDK5RAP2 Products
: "VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling." in: The Journal of clinical investigation, Vol. 121, Issue 8, pp. 3071-87, (2011) (PubMed).: "Casein kinase I delta controls centrosome positioning during T cell activation." in: The Journal of cell biology, Vol. 195, Issue 5, pp. 781-97, (2011) (PubMed).
: "Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors." in: Development (Cambridge, England), Vol. 137, Issue 11, pp. 1907-17, (2010) (PubMed).
: "CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response." in: The Journal of cell biology, Vol. 189, Issue 1, pp. 23-39, (2010) (PubMed).
Synonyms and alternative names related to CDK5RAP2
CDK5 regulatory subunit associated protein 2 (CDK5RAP2), CDK5 regulatory subunit-associated protein 2 (LOC100156240), CDK5 regulatory subunit associated protein 2 (cdk5rap2), CDK5 regulatory subunit associated protein 2 (Cdk5rap2), 2900018K03Rik, an, C48, Cep215, EGFL5, MCPH3, mKIAA1633Protein level used designations for CDK5RAP2
- CDK5 regulatory subunit-associated protein 2
- EGF-like-domain, multiple 5
- CDK5 regulatory subunit associated protein 2
- CDK5 regulatory subunit-associated protein 2-like
- CDK5 activator-binding protein C48
- centrosomal protein 215 kDa
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