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CDCP1 产品

(CUB Domain Containing Protein 1 (CDCP1))

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The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Featured CDCP1 Categories

CDCP1 抗体

High quality antibodies with extensive validation data.

CDCP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CDCP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDCP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7434047
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7073600
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN3187811
Quantity 100 μL
Datasheet Datasheet

Recommended CDCP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955136
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1568906
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5692215
Quantity 96 tests
Datasheet Datasheet

Recommended CDCP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274293
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274295
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274291
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CDCP1 Products

Sandercock, Rust, Guillard, Sachsenmeier, Holoweckyj, Hay, Flynn, Huang, Yan, Herpers, Price, Soden, Freeth, Jermutus, Hollingsworth, Minter: "Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling." in: Molecular cancer, Vol. 14, pp. 147, (2015) (PubMed).

Iwata, Torok-Storb, Wayner, Carter: "CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production." in: PLoS ONE, Vol. 9, Issue 10, pp. e109304, (2014) (PubMed).

Sasaroli, Gimotty, Pathak, Hammond, Kougioumtzidou, Katsaros, Buckanovich, Devarajan, Sandaltzopoulos, Godwin, Scholler, Coukos: "Novel surface targets and serum biomarkers from the ovarian cancer vasculature." in: Cancer biology & therapy, Vol. 12, Issue 3, pp. 169-80, (2011) (PubMed).

Kelly, Chan, Martinson, Kadoya, Ostertag, Ross, Richardson, Carpenter, DAmour, Kroon, Moorman, Baetge, Bang: "Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells." in: Nature biotechnology, Vol. 29, Issue 8, pp. 750-6, (2011) (PubMed).

He, Wortmann, Burke, Reid, Adams, Abdul-Jabbar, Quigley, Leduc, Kirchhofer, Hooper et al.: "Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain ..." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26162-73, (2010) (PubMed).

Hooper, Zijlstra, Aimes, Liang, Claassen, Tarin, Testa, Quigley: "Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen." in: Oncogene, Vol. 22, Issue 12, pp. 1783-94, (2003) (PubMed).

Synonyms and alternative names related to CDCP1

CUB domain containing protein 1 (CDCP1), CUB domain containing protein 1 (Cdcp1), CUB domain containing protein 1a (cdcp1a), 9030022E12Rik, AA409659, CD318, E030027H19Rik, RGD1305578, SIMA135, TRASK, zgc:113071

Protein level used designations for CDCP1

  • CUB domain-containing protein 1
  • membrane glycoprotein gp140
  • subtractive immunization M plus HEp3-associated 135 kDa protein
  • transmembrane and associated with src kinases
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