CD68 产品
(CD68 Molecule (CD68))
Categories
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured CD68 Categories
CD68 抗体
High quality antibodies with extensive validation data.
CD68 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CD68 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD68 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC (p), IHC (fro)
Validations
- (34)
- (10)
Cat. No.
ABIN3044428
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, IHC, ELISA, ICC
Validations
- (1)
- (8)
Cat. No.
ABIN2682982
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC (p), ICC, IF (p), IF (cc)
Validations
- (20)
- (3)
Cat. No.
ABIN671406
Quantity
100 μL
Datasheet
Datasheet
Recommended CD68 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965602
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965604
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965603
Quantity
96 tests
Datasheet
Datasheet
Recommended CD68 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN5854759
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348684
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092757
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD68 Products
: "Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice." in: Journal of biomechanics, Vol. 141, pp. 111179, (2022) (PubMed).: "Industrial Processing Induces Pericardial Patch Degeneration." in: Frontiers in surgery, Vol. 9, pp. 881433, (2022) (PubMed).
: "Mobilization of CD11b+/Ly6chi monocytes causes multi organ dysfunction syndrome in acute pancreatitis." in: Frontiers in immunology, Vol. 13, pp. 991295, (2022) (PubMed).
: "Elevated IL-15 concentrations in the sarcoidosis lung is independent of granuloma burden and disease phenotypes." in: American journal of physiology. Lung cellular and molecular physiology, (2021) (PubMed).
: "Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution." in: Cell death & disease, Vol. 12, Issue 6, pp. 589, (2021) (PubMed).
: "Exosomal miR-409-3p secreted from activated mast cells promotes microglial migration, activation and neuroinflammation by targeting Nr4a2 to activate the NF-κB pathway." in: Journal of neuroinflammation, Vol. 18, Issue 1, pp. 68, (2021) (PubMed).
: "Valproic Acid-Like Compounds Enhance and Prolong the Radiotherapy Effect on Breast Cancer by Activating and Maintaining Anti-Tumor Immune Function." in: Frontiers in immunology, Vol. 12, pp. 646384, (2021) (PubMed).
: "Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in microglia." in: Acta pharmacologica Sinica, Vol. 42, Issue 7, pp. 1069-1079, (2021) (PubMed).
: "Synergistic effects of AAGL and anti-PD-1 on hepatocellular carcinoma through lymphocyte recruitment to the liver." in: Cancer biology & medicine, (2021) (PubMed).
: "Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy." in: Redox biology, Vol. 38, pp. 101774, (2021) (PubMed).
Synonyms and alternative names related to CD68
CD68 molecule (CD68), CD68 antigen (Cd68), Cd68 molecule (Cd68), gp110, GP110, Lamp4, LAMP4, Scard1, SCARD1Protein level used designations for CD68
- macrosialin
- CD68 antigen
- macrophage antigen CD68
- scavenger receptor class D, member 1
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