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CD47 产品

(CD47)

Categories

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].

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Featured CD47 Categories

CD47 抗体

High quality antibodies with extensive validation data.

CD47 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CD47 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD47 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IF, IHC, ELISA, StM, Coat
Validations
  • (6)
Cat. No. ABIN6941215
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, IF, IHC, StM
Validations
  • (6)
Cat. No. ABIN6941211
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC
Validations
  • (7)
Cat. No. ABIN3022624
Quantity 100 μL
Datasheet Datasheet

Recommended CD47 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975258
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954524
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954525
Quantity 96 tests
Datasheet Datasheet

Recommended CD47 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (7)
Cat. No. ABIN7274225
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
Cat. No. ABIN7274220
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus, Rhesus Monkey
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274217
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD47 Products

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Wang, Sun, Zhou, Chen, Jiao, Li, Gou, Li, Du, Chen, Zhai, Wu, Qi, Gao: "CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 8, Issue 2, (2020) (PubMed).

Wang, Huang, Zhang, Liu, Liang, Jiang, Jiang, Yu, Jiang, Li, Zhang, Wen, Zheng: "Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma." in: Cancer medicine, Vol. 8, Issue 3, pp. 1315-1325, (2019) (PubMed).

Logtenberg, Jansen, Raaben, Toebes, Franke, Brandsma, Matlung, Fauster, Gomez-Eerland, Bakker, van der Schot, Marijt, Verdoes, Haanen, van den Berg, Neefjes, van den Berg, Brummelkamp, Leusen et al.: "Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. ..." in: Nature medicine, Vol. 25, Issue 4, pp. 612-619, (2019) (PubMed).

Josifovska, Szabó, Nagymihály, Veréb, Facskó, Eriksen, Moe, Petrovski: "Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy." in: Contact lens & anterior eye : the journal of the British Contact Lens Association, Vol. 40, Issue 5, pp. 283-292, (2018) (PubMed).

Ye, Wang, Lu, Zhang, Chen, Zhou: "CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma." in: Oncology letters, Vol. 15, Issue 6, pp. 9075-9080, (2018) (PubMed).

Davis, Kiss, Trivedi, Metzner, Liao, Gambhir: "Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype." in: ACS nano, Vol. 12, Issue 10, pp. 9669-9679, (2018) (PubMed).

Yu, Qiu, Long, Yang, Zhang, Xu, Chang, Du, Hou, Yu, Zeng, Wang, Sun: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).

Weiskopf: "Cancer immunotherapy targeting the CD47/SIRPα axis." in: European journal of cancer (Oxford, England : 1990), Vol. 76, pp. 100-109, (2017) (PubMed).

Kojima, Volkmer, McKenna, Civelek, Lusis, Miller, Direnzo, Nanda, Ye, Connolly, Schadt, Quertermous, Betancur, Maegdefessel, Matic, Hedin, Weissman, Leeper: "CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis." in: Nature, Vol. 536, Issue 7614, pp. 86-90, (2016) (PubMed).

Synonyms and alternative names related to CD47

alkaline phosphatase, intestinal (ALPI), CD47 molecule (CD47), CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47), Cd47 molecule (Cd47), 9130415E20Rik, AA407862, AI848868, AW108519, B430305P08Rik, CD47/IAP, IAP, Itgp, MER6, OA3

Protein level used designations for CD47

  • Kasahara isozyme
  • alkaline phosphomonoesterase
  • glycerophosphatase
  • intestinal alkaline phosphatase
  • intestinal-type alkaline phosphatase
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
  • CD47 glycoprotein
  • Rh-related antigen
  • antigen identified by monoclonal antibody 1D8
  • antigenic surface determinant protein OA3
  • integrin associated protein
  • integrin-associated protein
  • integrin-associated signal transducer
  • leukocyte surface antigen CD47
  • IAP
  • CD47 antigen
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