CD45 产品
(Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
Categories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012].
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Featured CD45 Categories
CD45 抗体
High quality antibodies with extensive validation data.
CD45 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CD45 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD45 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rabbit, Rat
Application
FACS, WB, IHC (p), ELISA, IF (p), IF (cc)
Validations
- (6)
- (6)
Cat. No.
ABIN669606
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
FACS, IHC, WB, StM
Validations
- (1)
- (6)
Cat. No.
ABIN6940460
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (6)
Cat. No.
ABIN7436852
Quantity
100 μL
Datasheet
Datasheet
Recommended CD45 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971252
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969754
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958959
Quantity
96 tests
Datasheet
Datasheet
Recommended CD45 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275500
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275499
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275501
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD45 Products
: "Fibroadipogenic progenitor cell response peaks prior to progressive fatty infiltration after rotator cuff tendon tear." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2022) (PubMed).: "Investigation of canine extracellular vesicles in diffuse large B-cell lymphomas." in: PloS one, Vol. 17, Issue 9, pp. e0274261, (2022) (PubMed).
: "A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon." in: EBioMedicine, Vol. 56, pp. 102819, (2021) (PubMed).
: "Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis." in: Frontiers in immunology, Vol. 11, pp. 607442, (2021) (PubMed).
: "Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation." in: Viruses, Vol. 12, Issue 4, (2021) (PubMed).
: "Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40." in: Cardiovascular therapeutics, Vol. 2020, pp. 1795853, (2021) (PubMed).
: "A novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation." in: Genome biology, Vol. 21, Issue 1, pp. 228, (2021) (PubMed).
: "Characterisation of stemness and multipotency of ovine muscle-derived stem cells from various muscle sources." in: Journal of anatomy, Vol. 239, Issue 2, pp. 336-350, (2021) (PubMed).
: "Attenuating Neurogenic Sympathetic Hyperreflexia Robustly Improves Antibacterial Immunity After Chronic Spinal Cord Injury." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 40, Issue 2, pp. 478-492, (2020) (PubMed).
: "Enhancing the antitumor activity of an engineered TRAIL-coated oncolytic adenovirus for treating acute myeloid leukemia." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 40, (2020) (PubMed).
Synonyms and alternative names related to CD45
protein tyrosine phosphatase, receptor type C (PTPRC), protein tyrosine phosphatase, receptor type, C (ptprc), receptor-type tyrosine-protein phosphatase C (LOC100074271), protein tyrosine phosphatase, receptor type, C (Ptprc), B220, CD45, Cd45, cd45, CD45R, GP180, L-CA, LCA, Lca, loc, Ly-5, LY5, Lyt-4, PTPRC, RT7, si:dkeyp-47c5.1, T200Protein level used designations for CD45
- receptor-type tyrosine-protein phosphatase C
- leukocyte common antigen, CD45
- protein tyrosine phosphatase, receptor type, C
- CD45 antigen
- leukocyte common antigen
- receptor-type tyrosine-protein phosphatase C-like
- T200 glycoprotein
- T200 leukocyte common antigen
- protein tyrosine phosphatase, receptor type, c polypeptide
- lymphocyte antigen 5
- lymphocyte common antigen
- Protein tyrosine phosphatase, receptor-type, c polypeptide
- leucocyte common antigen
- leukocyte common antigen A
- leukocyte common antigen B
- membrane tyrosine phosphatase
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