CD3E (Muromonab Biosimilar) 抗体
(CD3E (Muromonab Biosimilar))
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
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Recommended CD3E (Muromonab Biosimilar) 抗体
Synonyms and alternative names related to CD3E (Muromonab Biosimilar)
CD3e molecule (CD3E), T3E, TCREProtein level used designations for CD3E (Muromonab Biosimilar)
- CD3-epsilon
- CD3e antigen, epsilon polypeptide (TiT3 complex)
- T-cell antigen receptor complex, epsilon subunit of T3
- T-cell surface antigen T3/Leu-4 epsilon chain
- T-cell surface glycoprotein CD3 epsilon chain
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