CD33 (Gemtuzumab Biosimilar) 抗体
(CD33 (Gemtuzumab Biosimilar))
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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Recommended CD33 (Gemtuzumab Biosimilar) 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, IF
Validations
- (1)
Cat. No.
ABIN5668211
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (1)
Cat. No.
ABIN6964428
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, IF
Validations
Cat. No.
ABIN5668210
Quantity
200 μg
Datasheet
Datasheet
Synonyms and alternative names related to CD33 (Gemtuzumab Biosimilar)
CD33 molecule (CD33), p67, SIGLEC-3, SIGLEC3Protein level used designations for CD33 (Gemtuzumab Biosimilar)
- CD33 antigen (gp67)
- gp67
- myeloid cell surface antigen CD33
- sialic acid binding Ig-like lectin 3
- sialic acid-binding Ig-like lectin 3
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