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CD33 产品

(CD33)

Categories

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

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Featured CD33 Categories

CD33 抗体

High quality antibodies with extensive validation data.

CD33 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CD33 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD33 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), ICC, IHC (p)
Validations
  • (5)
  • (6)
Cat. No. ABIN687607
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC
Validations
  • (2)
  • (7)
Cat. No. ABIN1724812
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7440323
Quantity 100 μL
Datasheet Datasheet

Recommended CD33 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965566
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965565
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965567
Quantity 96 tests
Datasheet Datasheet

Recommended CD33 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274159
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275588
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274160
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD33 Products

Falk, Yazbeck, Guibert, Chamorey, Paquet, Ribeyre, Bence, Zahaf, Leroy, Marquette, Cohen, Mograbi, Mazières, Hofman, Brest, Hofman, Ilié: "Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients." in: Lung cancer (Amsterdam, Netherlands), Vol. 121, pp. 70-75, (2019) (PubMed).

Son, Diamond, Volpe, Aranow, Mackay, Santiago-Schwarz: "Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression." in: Scientific reports, Vol. 7, Issue 1, pp. 270, (2017) (PubMed).

Hagemann, Wickstroem, Wang, Shea, Sponheim, Karlsson, Bjerke, Ryan, Cuthbertson: "In Vitro and In Vivo Efficacy of a Novel CD33-Targeted Thorium-227 Conjugate for the Treatment of Acute Myeloid Leukemia." in: Molecular cancer therapeutics, Vol. 15, Issue 10, pp. 2422-2431, (2016) (PubMed).

Vyas, Schneider, Shatnyeva, Reiners, Tawadros, Kloess, Köhl, Hallek, Hansen, Pogge von Strandmann: "Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia." in: Oncoimmunology, Vol. 5, Issue 9, pp. e1211220, (2016) (PubMed).

Zhou, Ma, Zhou, Jiang, Rao, Zhao, Guo: "miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells." in: International journal of oncology, Vol. 48, Issue 4, pp. 1737-48, (2016) (PubMed).

Shan, Bu, Zhang, Zhang, Ding, Chang, Dai, Shen, Ma: "LukS-PV, a component of Panton-Valentine leukocidin, exerts potent activity against acute myeloid leukemia in vitro and in vivo." in: The international journal of biochemistry & cell biology, Vol. 61C, pp. 20-28, (2015) (PubMed).

Iwami, Brinkman, Bromberg: "Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics." in: Transplantation, Vol. 99, Issue 4, pp. 668-77, (2015) (PubMed).

Jiang, Li, Shi, Wu, An, Yang, Xu: "Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells." in: Cell death & disease, Vol. 5, pp. e1270, (2015) (PubMed).

Ishida, Akita, Mori, Tanida, Toda, Inoue, Nakada: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." in: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).

Shi, Jiang, Li, Shan, Li, An, Yang, Xu: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." in: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).

Synonyms and alternative names related to CD33

CD33 molecule (CD33), CD33 antigen (Cd33), CD33 molecule (Cd33), gp67, p67, SIGLEC-3, Siglec-3, SIGLEC3

Protein level used designations for CD33

  • CD33 antigen (gp67)
  • gp67
  • myeloid cell surface antigen CD33
  • sialic acid binding Ig-like lectin 3
  • sialic acid-binding Ig-like lectin 3
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