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CD1b 产品

(CD1b (CD1B))

Categories

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008].

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Featured CD1b Categories

CD1b 抗体

High quality antibodies with extensive validation data.

CD1b 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD1b 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IP, IHC (fro), IHC (p)
Validations
  • (3)
  • (4)
Cat. No. ABIN1981866
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5611269
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5611268
Quantity 100 μL
Datasheet Datasheet

Recommended CD1b 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122194
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348554
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348556
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CD1b Products

Lertjuthaporn, Khowawisetsut, Keawvichit, Polsrila, Chuansumrit, Chokephaibulkit, Thitilertdecha, Onlamoon, Ansari, Pattanapanyasat: "Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200564, (2018) (PubMed).

Saalmüller, Aasted: "Summary of the animal homologue section of HLDA8." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 2-13, (2007) (PubMed).

Andersson, Samarina, Fink, Rahman, Grundström: "Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis." in: Infection and immunity, Vol. 75, Issue 11, pp. 5210-22, (2007) (PubMed).

Groot, Geijtenbeek, Sanders, Baldwin, Sanchez-Hernandez, Floris, van Kooyk, de Jong, Berkhout: "Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction." in: Journal of virology, Vol. 79, Issue 5, pp. 3009-15, (2005) (PubMed).

Semnani, Law, Kubofcik, Nutman: "Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6229-38, (2004) (PubMed).

Higashi, Morikawa, Fujioka, Fujita, Sano, Miyata-Takeuchi, Suzuki, Irimura: "Human macrophage lectin specific for galactose/N-acetylgalactosamine is a marker for cells at an intermediate stage in their differentiation from monocytes into macrophages." in: International immunology, Vol. 14, Issue 6, pp. 545-54, (2002) (PubMed).

Saito, Kametani, Hozumi, Mochida, Ando, Ito, Nomura, Tokuda, Makuuchi, Tajima, Habu: "The in vivo development of human T cells from CD34(+) cells in the murine thymic environment." in: International immunology, Vol. 14, Issue 10, pp. 1113-24, (2002) (PubMed).

Bakri, Schiffer, Zennou, Charneau, Kahn, Benjouad, Gluckman, Canque: "The maturation of dendritic cells results in postintegration inhibition of HIV-1 replication." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 6, pp. 3780-8, (2001) (PubMed).

Niazi, Chiu, Mendoza, Degano, Khurana, Moody, Melián, Wilson, Kronenberg, Porcelli, Modlin: "The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 4, pp. 2562-70, (2001) (PubMed).

Giuliani, Prete, Graziani, Aquino, Balduzzi, Sugita, Brenner, Iona, Fattorini, Orefici, Porcelli, Bonmassar: "Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells." in: Infection and immunity, Vol. 69, Issue 12, pp. 7461-70, (2001) (PubMed).

Synonyms and alternative names related to CD1b

CD1b molecule (CD1B), T-cell surface glycoprotein CD1b-3 (LOC443423), CD1b1 molecule (CD1B1), T-cell surface glycoprotein CD1b1 (LOC100720602), CD1, CD1-b, CD1A, CD1B, CD1B3, R1

Protein level used designations for CD1b

  • CD1B antigen, b polypeptide
  • T-cell surface glycoprotein CD1b
  • cortical thymocyte antigen CD1B
  • differentiation antigen CD1-alpha-3
  • CD1b3
  • CD1b molecule
  • T-cell surface glycoprotein CD1b-3
  • CD1b antigen
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