CD160 产品
(CD160)
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CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008].
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Featured CD160 Categories
CD160 抗体
High quality antibodies with extensive validation data.
CD160 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CD160 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD160 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS
Validations
- (4)
- (4)
Cat. No.
ABIN1981901
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, FACS, ELISA, IF (p), IHC (p)
Validations
- (4)
Cat. No.
ABIN741555
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, IP
Validations
- (2)
- (3)
Cat. No.
ABIN2749166
Quantity
0.1 mg
Datasheet
Datasheet
Recommended CD160 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954489
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730431
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5690842
Quantity
96 tests
Datasheet
Datasheet
Recommended CD160 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274073
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274082
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274093
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD160 Products
: "Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1838-48, (2015) (PubMed).: "CD160 isoforms and regulation of CD4 and CD8 T-cell responses." in: Journal of translational medicine, Vol. 12, pp. 217, (2015) (PubMed).
: "Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses." in: PLoS ONE, Vol. 9, Issue 2, pp. e88327, (2014) (PubMed).
: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
: "BY55/CD160 cannot be considered a cytotoxic marker in cytomegalovirus-specific human CD8(+) T cells." in: Clinical and experimental immunology, Vol. 149, Issue 1, pp. 87-96, (2007) (PubMed).
: "Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 6, pp. 2780-90, (1998) (PubMed).
: "BY55 monoclonal antibody delineates within human cord blood and bone marrow lymphocytes distinct cell subsets mediating cytotoxic activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 19, pp. 9136-40, (1994) (PubMed).
: "Differential expression of HLA class II antigens in fetal human spleen: relationship of HLA-DP, DQ, and DR to immunoglobulin expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 137, Issue 2, pp. 490-7, (1986) (PubMed).
: "Functional expression of HLA-DP genes transfected into mouse fibroblasts." in: Nature, Vol. 313, Issue 5997, pp. 61-4, (1985) (PubMed).
: "Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia." in: Transplantation proceedings, Vol. 13, Issue 1 Pt 2, pp. 761-6, (1981) (PubMed).
Synonyms and alternative names related to CD160
CD160 molecule (CD160), CD160 molecule (Cd160), CD160 antigen (Cd160), AU045688, BY55, By55, CD160, NK1, NK28, RGD1563598Protein level used designations for CD160
- CD160 molecule
- CD160 antigen
- natural killer cell BY55
- natural killer cell receptor BY55
- CD160 transmembrane isoform
- CD160-delta Ig
- natural killer cell receptor, immunoglobulin superfamily member
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