CD16 / CD56 抗体
(CD16 / CD56)
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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CD16 / CD56 抗体
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Synonyms and alternative names related to CD16 / CD56
Fc fragment of IgG receptor IIIa (FCGR3A), CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3Protein level used designations for CD16 / CD56
- CD16a antigen
- Fc fragment of IgG, low affinity III, receptor for (CD16)
- Fc gamma receptor III-A
- Fc-gamma RIII-alpha
- Fc-gamma RIIIa
- Fc-gamma receptor III-2 (CD 16)
- Fc-gamma receptor IIIb (CD16)
- FcgammaRIIIA
- fc-gamma RIII
- igG Fc receptor III-2
- immunoglobulin G Fc receptor III
- low affinity immunoglobulin gamma Fc region receptor III-A
- neutrophil-specific antigen NA
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