CCR3 产品
(Chemokine (C-C Motif) Receptor 3 (CCR3))
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The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009].
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Featured CCR3 Categories
CCR3 抗体
High quality antibodies with extensive validation data.
CCR3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CCR3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
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Application
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Cat. No.
ABIN5611257
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
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Cat. No.
ABIN738651
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Cat. No.
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Recommended CCR3 ELISA试剂盒
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ABIN6965709
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Latest Publications for our CCR3 Products
: "Crucial role of OX40/OX40L signaling in a murine model of asthma." in: Molecular medicine reports, Vol. 17, Issue 3, pp. 4213-4220, (2018) (PubMed).: "Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 33, pp. E4837-46, (2016) (PubMed).
: "CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice." in: PLoS ONE, Vol. 11, Issue 11, pp. e0165595, (2016) (PubMed).
: "Late IL-3-induced phenotypic and functional alterations in human basophils require continuous IL-3 receptor signaling." in: Journal of leukocyte biology, Vol. 101, Issue 1, pp. 227-238, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
: "Expression and prognostic significance of CCL11/CCR3 in glioblastoma." in: Oncotarget, Vol. 7, Issue 22, pp. 32617-27, (2016) (PubMed).
: "Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells." in: Scientific reports, Vol. 6, pp. 27152, (2016) (PubMed).
: "Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157186, (2016) (PubMed).
: "Generation of eosinophils from cryopreserved murine bone marrow cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e116141, (2015) (PubMed).
: "Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge." in: The Journal of allergy and clinical immunology, Vol. 135, Issue 2, pp. 451-60, (2015) (PubMed).
Synonyms and alternative names related to CCR3
C-C motif chemokine receptor 3 (CCR3), chemokine (C-C motif) receptor 3 (Ccr3), C-C motif chemokine receptor 3 (Ccr3), CC-CKR-3, CC-CKR3, CD193, CKR3, Cmkbr1l2, CMKBR3, Cmkbr3Protein level used designations for CCR3
- C-C CKR-3
- C-C chemokine receptor type 3
- CC chemokine receptor 3
- CCR-3
- b-chemokine receptor
- eosinophil CC chemokine receptor 3
- eosinophil eotaxin receptor
- CC-CKR-3
- MIP-1 alpha RL2
- MIP-1 alphaRL2
- chemokine (C-C) receptor 1,-like 2
- chemokine (C-C) receptor 3
- macrophage inflammatory protein 1-alpha receptor-like 2
- probable C-C chemokine receptor type 3
- CKR3
- C-C chemokine receptor 3
- eotaxin receptor CCR3
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