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CCR1 产品

(Chemokine (C-C Motif) Receptor 1 (CCR1))
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008].

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Featured CCR1 Categories

CCR1 抗体

High quality antibodies with extensive validation data.

CCR1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CCR1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCR1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5611255
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3030216
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7145918
Quantity 100 μg
Datasheet Datasheet

Recommended CCR1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965707
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954643
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954644
Quantity 96 tests
Datasheet Datasheet

Recommended CCR1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7491555
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2565240
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964237
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CCR1 Products

Huang, Li, Pan, Cheng, Ren, Jia, Ma, Xu: "A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis." in: Oncotarget, Vol. 7, Issue 36, pp. 57705-57713, (2018) (PubMed).

Sun, Chen, Lin, Chen, Yu, Hou, Li: "Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain." in: Molecular immunology, Vol. 77, pp. 184-92, (2016) (PubMed).

Williams, José, Mercer, Brealey, Parekh, Thickett, OKane, McAuley, Chambers: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).

Fleming, Chandrasekaran, Dillon, Dalby, Suresh, Sarkar, El-Sayed, Mosser: "The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling." in: Journal of leukocyte biology, Vol. 98, Issue 3, pp. 395-407, (2015) (PubMed).

Broux, Mizee, Vanheusden, van der Pol, van Horssen, Van Wijmeersch, Somers, de Vries, Stinissen, Hellings: "IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 5, pp. 2099-109, (2015) (PubMed).

Geng, Kaczanowska, Tsai, Younger, Ochoa, Rapoport, Ostrand-Rosenberg, Davila: "TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity." in: Cancer research, Vol. 75, Issue 10, pp. 1959-71, (2015) (PubMed).

de la Rica, García-Gómez, Comet, Rodríguez-Ubreva, Ciudad, Vento-Tormo, Company, Álvarez-Errico, García, Gómez-Vaquero, Ballestar: "NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation." in: Genome biology, Vol. 16, pp. 2, (2015) (PubMed).

Lewis, Muthukumarana, Fogal, Corradini, Stefanopoulos, Adusumalli, Pelletier, Panzenbeck, Berg, Canfield, Cook, Razavi, Kuzmich, Anderson, Allard, Harrison, Grimaldi, Souza, Harcken, Fryer, Modis et al.: "CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells. ..." in: PLoS ONE, Vol. 9, Issue 8, pp. e105883, (2015) (PubMed).

Parlet, Schlueter: "Mechanisms by which chronic ethanol feeding impairs the migratory capacity of cutaneous dendritic cells." in: Alcoholism, clinical and experimental research, Vol. 37, Issue 12, pp. 2098-107, (2013) (PubMed).

Soehnlein, Drechsler, Döring, Lievens, Hartwig, Kemmerich, Ortega-Gómez, Mandl, Vijayan, Projahn, Garlichs, Koenen, Hristov, Lutgens, Zernecke, Weber: "Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes." in: EMBO molecular medicine, Vol. 5, Issue 3, pp. 471-81, (2013) (PubMed).

Synonyms and alternative names related to CCR1

C-C motif chemokine receptor 1 (CCR1), chemokine (C-C motif) receptor 1 (Ccr1), C-C motif chemokine receptor 1 (Ccr1), CD191, CKR-1, CKR1, CMKBR1, Cmkbr1, HM145, Mip-1a-R, MIP1aR, SCYAR1

Protein level used designations for CCR1

  • C-C CKR-1
  • C-C chemokine receptor type 1
  • CC-CKR-1
  • CCR-1
  • LD78 receptor
  • MIP-1alpha-R
  • RANTES receptor
  • RANTES-R
  • macrophage inflammatory protein 1-alpha receptor
  • MIP-1 alpha R
  • MIP-1 alphaR
  • chemokine (C-C) receptor 1
  • macrophage inflammatory protein-1 alpha receptor
  • chemokine receptor
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