CBX8 产品
(Chromobox Homolog 8 (CBX8))
Categories
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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Featured CBX8 Categories
Recommended CBX8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN1724766
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN1724765
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN7147709
Quantity
100 μL
Datasheet
Datasheet
Recommended CBX8 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348218
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090750
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3130472
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CBX8 Products
: "CBX8 antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-E2F1 pathway in K562 leukemia cells." in: Biochemical and biophysical research communications, Vol. 469, Issue 4, pp. 884-90, (2016) (PubMed).: "Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor." in: The EMBO journal, Vol. 29, Issue 15, pp. 2553-65, (2010) (PubMed).
: "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties." in: The Journal of biological chemistry, Vol. 275, Issue 37, pp. 28785-92, (2000) (PubMed).
Synonyms and alternative names related to CBX8
chromobox 8 (cbx8), chromobox 8 (CBX8), chromobox 8 (Cbx8), chromobox 8 S homeolog (cbx8.S), chromobox homolog 8a (Pc class homolog, Drosophila) (cbx8a), cbx8, MGC147589, Pc3, PC3, RC1Protein level used designations for CBX8
- chromobox homolog 8
- chromobox protein homolog 8
- mPc3
- polycomb 3 homolog
- Pc class 3 homolog
- chromobox homolog 8 (Pc class homolog, Drosophila)
- polycomb 3
- rectachrome 1
- chromobox-like protein 8
- chromobox homolog 8 (Pc class homolog)
- chromobox homolog 8a
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