CBX5 产品
(Chromobox Homolog 5 (CBX5))
Categories
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
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Featured CBX5 Categories
CBX5 抗体
High quality antibodies with extensive validation data.
CBX5 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CBX5 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CBX5 抗体
Product
Reactivity
Application
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Cat. No.
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Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
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- (6)
Cat. No.
ABIN7101571
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS
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- (8)
Cat. No.
ABIN185491
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, ICC, FACS
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- (8)
Cat. No.
ABIN5542711
Quantity
100 μL
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Datasheet
Recommended CBX5 ELISA试剂盒
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Cat. No.
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Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648334
Quantity
96 tests
Datasheet
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Reactivity
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Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951753
Quantity
96 tests
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Recommended CBX5 蛋白
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Reactivity
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Datasheet
Reactivity
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Source
Escherichia coli (E. coli)
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- (1)
Cat. No.
ABIN7122366
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348213
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505415
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CBX5 Products
: "Arginine methylation expands the regulatory mechanisms and extends the genomic landscape under E2F control." in: Science advances, Vol. 5, Issue 6, pp. eaaw4640, (2019) (PubMed).: "Isolation of In Vivo SUMOylated Chromatin-Bound Proteins." in: Methods in molecular biology (Clifton, N.J.), Vol. 1475, pp. 205-16, (2016) (PubMed).
: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
: "SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase." in: Cell reports, Vol. 13, Issue 6, pp. 1183-93, (2015) (PubMed).
: "Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damage." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 34024-32, (2014) (PubMed).
: "Antagonism of bradykinin B2 receptor prevents inflammatory responses in human endothelial cells by quenching the NF-kB pathway activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e84358, (2014) (PubMed).
: "Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 43, pp. 17466-71, (2012) (PubMed).
: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).
: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).
: "Transcription factor YY1 associates with pericentromeric gamma-satellite DNA in cycling but not in quiescent (G0) cells." in: Nucleic acids research, Vol. 32, Issue 14, pp. 4390-9, (2004) (PubMed).
Synonyms and alternative names related to CBX5
chromobox 5 (CBX5), chromobox homolog 5 (HP1 alpha homolog, Drosophila) (cbx5), chromobox 5 (Cbx5), chromobox 5 S homeolog (cbx5.S), chromobox 5 (cbx5), 2610029O15Rik, C75991, CBX5, cbx5, HP1, HP1A, Hp1a, Hp1alpha, id:ibd2026, MGC64354, wu:fc63e02, wu:fe47g12, wu:fi03h05, zgc:158601Protein level used designations for CBX5
- HP1 alpha homolog
- HP1-ALPHA
- HP1Hs alpha
- antigen p25
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox protein homolog 5
- heterochromatin protein 1 homolog alpha
- heterochromatin protein 1-alpha
- fc63e02
- chromobox-like protein 5
- chromobox-like protein 5 (HP1 alpha homolog, Drosophila)
- HP1 alpha
- chromobox homolog 5
- heterochromatin protein 1 alpha
- mHP1(alpha)
- chromobox homolog 5 tv3
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