CBX3 抗体
(Chromobox Homolog 3 (CBX3))
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011].
recommended
Verified CBX3 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
recommended
recommended
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Latest Publications for our CBX3 抗体
: "Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1? at chromatin." in: Molecular and cellular biology, Vol. 34, Issue 19, pp. 3662-74, (2014) (PubMed).: "Somatostatin derivative (smsDX) targets cellular metabolism in prostate cancer cells after androgen deprivation therapy." in: PLoS ONE, Vol. 8, Issue 2, pp. e55790, (2013) (PubMed).
: "Knockdown of HMGA1 inhibits human breast cancer cell growth and metastasis in immunodeficient mice." in: Biochemical and biophysical research communications, Vol. 434, Issue 1, pp. 70-4, (2013) (PubMed).
: "Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis." in: Oncogene, Vol. 31, Issue 27, pp. 3287-97, (2012) (PubMed).
: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).
: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).
: "Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin." in: Molecular cell, Vol. 19, Issue 3, pp. 381-91, (2005) (PubMed).
: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).
: "Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family." in: The EMBO journal, Vol. 18, Issue 22, pp. 6385-95, (2000) (PubMed).
Aliases for CBX3 抗体
chromobox 3 (CBX3) 抗体chromobox 3 (Cbx3) 抗体
chromobox 3 L homeolog (cbx3.L) 抗体
chromobox protein homolog 3 pseudogene (LOC100355282) 抗体
chromobox homolog 3a (HP1 gamma homolog, Drosophila) (cbx3a) 抗体
cbx3 抗体
cbx3a 抗体
HECH 抗体
HP1-GAMMA 抗体
Hp1-gamma 抗体
HP1g 抗体
HP1Hs-gamma 抗体
M32 抗体
wu:fb61b02 抗体
xhp1g 抗体
zgc:153397 抗体
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