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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

(Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB))

E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways. In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production. Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation. In activated T- cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy. In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation. Slightly promotes SRC ubiquitination. May be involved in EGFR ubiquitination and internalization. May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3. {ECO:0000269|PubMed:10646608, ECO:0000269|PubMed:10646609, ECO:0000269|PubMed:11070165, ECO:0000269|PubMed:11526404, ECO:0000269|PubMed:12771181, ECO:0000269|PubMed:15308098}.

recommended

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (ABIN760256)

CBLB 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

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recommended

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (N-Term) 抗体 (ABIN6260515)

CBLB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

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recommended

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 1-350) 抗体 (ABIN3015830)

CBLB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 适用

Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 for a variety of species such as anti-Human Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase, anti-Mouse Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase, anti-Rat Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase. The species listed below are among those available. Click on a link to go to the corresponding products.

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 应用范围

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 抗体来源

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 抗原表位

Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 克隆形成能力

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 克隆

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 标记

Find Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体

Reactivity Human

Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)

Validations

Cat. No. ABIN760256

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (N-Term) 抗体

Reactivity Human, Mouse, Rat

Application WB, ELISA, IHC

Validations

Cat. No. ABIN6260515

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 1-350) 抗体

Reactivity Human

Application WB

Validations

Cat. No. ABIN3015830

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 103-130) 抗体

Reactivity Rat

Application WB, FACS, IHC (p)

Validations

Cat. No. ABIN652612

Quantity 400 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) 抗体

Reactivity Human

Application WB, IHC, FACS

Validations

Cat. No. ABIN3003861

Quantity 400 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (C-Term) 抗体

Reactivity Human

Application WB

Validations

Cat. No. ABIN2855378

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) 抗体

Reactivity Human

Application WB, DB

Validations

Cat. No. ABIN933045

Quantity 100 μg

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (Biotin)

Reactivity Human

Application WB, ELISA, IHC (p), IHC (fro)

Validations

Cat. No. ABIN760258

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 555)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN913847

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 647)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN913848

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 594)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN2806042

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 350)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN913845

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 488)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN913846

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 750)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN5009982

Quantity 100 μL

Datasheet Datasheet

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 101-200) 抗体 (AbBy Fluor® 680)

Reactivity Human

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN5009981

Quantity 100 μL

Datasheet Datasheet

Aliases for Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

Cbl proto-oncogene B, E3 ubiquitin protein ligase S homeolog (cblb.S) 抗体
Cbl proto-oncogene B, E3 ubiquitin protein ligase L homeolog (cblb.L) 抗体
Casitas B-lineage lymphoma b (Cblb) 抗体
Cbl proto-oncogene B (Cblb) 抗体
Cbl proto-oncogene B (CBLB) 抗体
AI429560 抗体
AI851073 抗体
Cbl-b 抗体
cblb 抗体
rnf56 抗体

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Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 适用

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 应用范围

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 抗体来源

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 抗原表位

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 克隆形成能力

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 克隆

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体 by 标记

Popular Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

Aliases for Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase 抗体

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